公开(公告)号：US10814022B2

公开(公告)日：2020-10-27

申请号：US15581295

申请日：2017-04-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sehoon Kim ,  Chang-Keun Lim ,  Jeong yun Heo ,  Keunsoo Jeong

IPC: A61K49/22 ,  A61K49/00 ,  G01N21/64 ,  A61K47/34

Abstract: The present invention relates to a nanogel comprising a polyamine-based polymer cross-linked by oxamide bonds, a preparation method of the nanogel, a contrast agent for ultrasound imaging comprising the nanogel, a composition for ultrasound diagnosis of inflammatory diseases comprising the contrast agent, a preparation method of the contrast agent, and a method for providing information for diagnosis of inflammatory diseases using the composition for ultrasound diagnosis.

公开(公告)号：US20180064832A1

公开(公告)日：2018-03-08

申请号：US15581295

申请日：2017-04-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sehoon Kim ,  Chang-Keun Lim ,  Jeong yun Heo ,  Keunsoo Jeong

IPC: A61K49/22 ,  A61K47/34

CPC classification number: A61K49/226 ,  A61K47/34 ,  G01N21/64

Abstract: The present invention relates to a nanogel comprising a polyamine-based polymer cross-linked by oxamide bonds, a preparation method of the nanogel, a contrast agent for ultrasound imaging comprising the nanogel, a composition for ultrasound diagnosis of inflammatory diseases comprising the contrast agent, a preparation method of the contrast agent, and a method for providing information for diagnosis of inflammatory diseases using the composition for ultrasound diagnosis.