公开(公告)号：US20170327518A1

公开(公告)日：2017-11-16

申请号：US15479150

申请日：2017-04-04

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jun-Seok LEE ,  Dhiraj P. MURALE ,  Seong-Cheol HONG ,  Seok LEE

IPC: C07F5/02 ,  C09K11/06 ,  C07F9/572 ,  C09B69/00 ,  G01N33/58

CPC classification number: C07F5/027 ,  C07F9/6561 ,  C09B23/04 ,  C09B69/001 ,  C09K11/06 ,  C09K2211/1433 ,  C09K2211/1466 ,  G01N33/582

Abstract: This invention relates to a compound for labeling mitochondria and a method of producing the same, wherein the compound is represented by Chemical Formula 1 or Chemical Formula 2 below, and is useful in labeling mitochondria. In Chemical Formulas 1 and 2, n is 4 or 10.

公开(公告)号：US20200040190A1

公开(公告)日：2020-02-06

申请号：US16403041

申请日：2019-05-03

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jun-Seok LEE ,  Dhiraj P. MURALE ,  Seong-Cheol HONG ,  Kyung-Tae HONG ,  Yun-Kyung KIM ,  Seok LEE

IPC: C09B23/04 ,  G01N21/64

Abstract: Disclosed is a fluorescent probe specifically labeling mitochondria, which can exhibit high transmittance by virtue of light emission in the NIR range and in which nonspecific fluorescence absorption in biomolecules can be avoided, making it possible to observe fluorescence images in deep tissue.