公开(公告)号：US12082500B2

公开(公告)日：2024-09-03

申请号：US15371066

申请日：2016-12-06

Applicant: Samsung Display Co., Ltd

Inventor： Junha Park ,  Youngkook Kim ,  Munki Sim ,  Eunyoung Lee ,  Hyoyoung Lee ,  Eunjae Jeong ,  Seokhwan Hwang

IPC: H10K85/60 ,  C07D221/18 ,  C07D401/10 ,  C07D405/10 ,  C07D471/04 ,  C07F9/576 ,  C07F9/6558 ,  C07F9/6561 ,  H10K50/16 ,  H10K50/17 ,  H10K50/18

CPC classification number: H10K85/6572 ,  C07D221/18 ,  C07D401/10 ,  C07D405/10 ,  C07D471/04 ,  C07F9/5765 ,  C07F9/65583 ,  C07F9/6561 ,  H10K85/626 ,  H10K85/654 ,  H10K85/6574 ,  H10K50/16 ,  H10K50/171 ,  H10K50/18

Abstract: Provided are a condensed cyclic compound and an organic light-emitting device. The condensed cyclic compound is represented by Formula 1:




Details about the constituents of Formula 1 is disclosed.

公开(公告)号：US20240279258A1

公开(公告)日：2024-08-22

申请号：US18594725

申请日：2024-03-04

Applicant: Forward Therapeutics, Inc.

Inventor： Toufike KANOUNI

IPC: C07F9/6561 ,  A61K9/08 ,  A61K9/48 ,  C07D471/02 ,  C07F9/6558 ,  C07F9/6584

CPC classification number: C07F9/6561 ,  A61K9/08 ,  A61K9/4825 ,  C07D471/02 ,  C07F9/65583 ,  C07F9/6584

Abstract: Provided herein are inhibitors of TNF-α, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the TNF-α inhibitory compounds for the treatment of diseases or disorders.

公开(公告)号：US20240248094A1

公开(公告)日：2024-07-25

申请号：US18425634

申请日：2024-01-29

Applicant: SONY GROUP CORPORATION

Inventor： Tracy MATRAY ,  Sharat SINGH

IPC: G01N33/58 ,  C07F9/09 ,  C07F9/572 ,  C07F9/576 ,  C07F9/6558 ,  C07F9/6561 ,  C09B3/14 ,  C09B11/26 ,  C09B69/10 ,  G01N33/52 ,  G01N33/533

CPC classification number: G01N33/582 ,  C07F9/091 ,  C07F9/572 ,  C07F9/65583 ,  C07F9/65586 ,  C07F9/6561 ,  C09B3/14 ,  C09B11/26 ,  C09B69/101 ,  C09B69/102 ,  C09B69/103 ,  C09B69/109 ,  G01N33/52 ,  G01N33/533 ,  C07F9/09 ,  C07F9/094 ,  C07F9/098 ,  C07F9/5765

Abstract: Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I):




or a stercoisomer, tantomer or salt thereof, wherein R1, R2, R3, R4, R5, L1, L2, L3, L4, M, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

公开(公告)号：US20240228521A1

公开(公告)日：2024-07-11

申请号：US18554795

申请日：2022-04-14

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： David SPERANDIO ,  Helena SHOMAR MONNGES ,  Eugene J. EISENBERG ,  Arthur MACHLENKIN

IPC: C07F9/6561 ,  A61K31/675

CPC classification number: C07F9/6561 ,  A61K31/675

Abstract: Disclosed herein are 3, 4-didehydro- and 3′-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof. The 3, 4-didehydro- and 3′-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof may be used in methods of treating diseases including virus-induced diseases, cancer, autoimmune diseases, immune disorders, and bacterial-associated diseases or infections, or combinations thereof. Examples of viral-induced diseases include viral infections by RNA or DNA viruses, for example SARS-CoV-2, EBV, and BKV.

公开(公告)号：US20240228503A1

公开(公告)日：2024-07-11

申请号：US18586620

申请日：2024-02-26

Applicant: GlaxoSmithKline Intellectual Property Development Limited

Inventor： Adam K. CHARNLEY ,  Janos BOTYANSZKI ,  Xiaoyang DONG ,  Philip Gareth HUMPHREYS ,  Bryan Wayne KING ,  Kimberly Katherine MARCUS ,  Joseph PERO ,  Alexander Joseph REIF ,  Daohua ZHANG ,  Attiq RAHMAN(Deceased) ,  Kenneth Allen NEWLANDER ,  Kenneth WIGGALL ,  Joshi RAMANJULU

IPC: C07D487/04 ,  C07D403/14 ,  C07D471/04 ,  C07D471/14 ,  C07F9/6561

CPC classification number: C07D487/04 ,  C07D403/14 ,  C07D471/04 ,  C07D471/14 ,  C07F9/6561

Abstract: The present invention relates to compounds, compositions containing them, and to their use in the treatment of various disorders, in particular autoimmune, autoinflammatory or immune-mediated conditions, such as systemic lupus erythematosus (SLE), cutaneous lupus erythematosus (CLE) and lupus nephritis.

公开(公告)号：US12030904B2

公开(公告)日：2024-07-09

申请号：US18301179

申请日：2023-04-14

Applicant: Gilead Sciences, Inc.

Inventor： Scott E. Lazerwith ,  Jonathan William Medley ,  Philip A. Morganelli ,  Devan Naduthambi ,  Thomas P. Stratton ,  Peiyuan Wang

IPC: C07F9/6561 ,  A61P31/12

CPC classification number: C07F9/6561 ,  A61P31/12

Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US12030903B2

公开(公告)日：2024-07-09

申请号：US17178115

申请日：2021-02-17

Applicant: Gilead Sciences, Inc.

Inventor： Daniel H. Byun ,  Gregory F. Chin ,  Michael O. Clarke ,  Bindu Goyal ,  Petr Jansa ,  Richard L. Mackman ,  Michael R. Mish ,  Dustin S. Siegel

IPC: C07F9/6561 ,  A61K45/06

CPC classification number: C07F9/6561 ,  A61K45/06

Abstract: The present disclosure describes 4′-fluoromethyl nucleosides for treating viral infections, including Dengue.

公开(公告)号：US20240217964A1

公开(公告)日：2024-07-04

申请号：US18283339

申请日：2022-03-22

Applicant: Newave Pharmaceutical Inc.

Inventor： Yi Chen

IPC: C07D453/02 ,  A61K31/439 ,  A61K31/4748 ,  A61K31/675 ,  A61P35/00 ,  C07D471/08 ,  C07F9/6561

CPC classification number: C07D453/02 ,  A61K31/439 ,  A61K31/4748 ,  A61K31/675 ,  A61P35/00 ,  C07D471/08 ,  C07F9/6561

Abstract: The disclosure includes compounds of either Formula (A), wherein R1, R2, R3, R4, m, n, k, r, s, t, and L are defined herein; or Formula (I), wherein R1, R2, R3, m, n, and k are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.

公开(公告)号：US12006331B2

公开(公告)日：2024-06-11

申请号：US17862963

申请日：2022-07-12

Applicant: GENENTECH, INC.

Inventor： Samantha Alyson Green ,  Jessica Marie Grandner ,  Steven Thomas Staben ,  Neri Amara ,  Vishva M. Dixit ,  Elisia Villemure

IPC: C07D498/04 ,  A61K9/08 ,  A61K9/12 ,  A61K9/20 ,  A61K9/48 ,  A61K47/02 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  C07D519/00 ,  C07F9/6561

CPC classification number: C07D498/04 ,  A61K9/08 ,  A61K9/12 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/485 ,  A61K9/4858 ,  A61K9/4866 ,  A61K47/02 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  C07D519/00 ,  C07F9/6561

Abstract: The invention provides a compound of formula (I):




or a prodrug thereof, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 have any of the values described in the specification, as well as compositions comprising a compound of formula (I) or a prodrug thereof, or a pharmaceutically acceptable salt thereof. The compounds are agonists of glycolytic enzyme phosphofructokinase-1 liver type and are useful for treating diseases associated with the activity of glycolytic enzyme phosphofructokinase-1 liver type, such as cancer, diabetes, sepsis, and septic shock.

公开(公告)号：US20240188315A1

公开(公告)日：2024-06-06

申请号：US18323647

申请日：2023-05-25

Applicant: Samsung Display Co., Ltd.

Inventor： Kyoung Sunwoo ,  Chanseok Oh ,  Sunyoung Pak ,  Munki Sim

IPC: H10K50/11 ,  C07D487/04 ,  C07F5/02 ,  C07F9/6561 ,  C09K11/06 ,  H10K50/15 ,  H10K50/16 ,  H10K50/18 ,  H10K50/81 ,  H10K50/82 ,  H10K85/60

CPC classification number: H10K50/11 ,  C07D487/04 ,  C07F5/027 ,  C07F9/6561 ,  C09K11/06 ,  H10K50/156 ,  H10K50/16 ,  H10K50/181 ,  H10K50/81 ,  H10K50/82 ,  H10K85/6572 ,  H10K85/658 ,  C09K2211/1018

Abstract: Embodiments provide a light-emitting device including a heterocyclic compound, and an electronic device including the light-emitting device. The light-emitting device includes a first electrode, a second electrode facing the first electrode, an interlayer between the first electrode and the second electrode and including an interlayer, and a heterocyclic compound. The heterocyclic compound is represented by Formula 1, which is explained in the specification: