公开(公告)号：US20240115515A1

公开(公告)日：2024-04-11

申请号：US18166782

申请日：2023-02-09

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Dae-Ro AHN ,  Kyoung-Ran KIM ,  Junghyun KIM ,  Ji Eun LEE ,  Ji hyun BACK

IPC: A61K9/51 ,  A61K47/54 ,  A61P1/16 ,  C12N15/113

CPC classification number: A61K9/5169 ,  A61K47/549 ,  A61P1/16 ,  C12N15/113

Abstract: The present invention relates to a liver-specific drug delivery carrier comprising a nucleic acid nanoparticle and cholesterol; a liver-specific complex; a pharmaceutical composition for prevention or treatment of liver disease using the same; and a method for preventing or treating liver disease.