公开(公告)号：US20170030913A1

公开(公告)日：2017-02-02

申请号：US15220521

申请日：2016-07-27

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  SAMSUNG LIFE PUBLIC WELFARE FOUNDATION

Inventor： Ji Eun LEE ,  Dong Huey CHEON ,  Cheolju LEE ,  Eun Gyeong YANG ,  Jihye SHIN ,  Hee Cheol KIM ,  Ji Hye HAN

IPC: G01N33/574

CPC classification number: G01N33/57419 ,  G01N2333/521

Abstract: Provided are a composition or a kit for diagnosing colorectal cancer including a CXCL7-measuring agent, and a method of diagnosing colorectal cancer using the same. According to the composition or the kit, and the method, colorectal cancer may be simply diagnosed with high diagnostic accuracy and specificity for colorectal cancer.

Abstract translation: 提供了用于诊断包括CXCL7测定剂的结肠直肠癌的组合物或试剂盒，以及使用该组合物或试剂盒诊断结肠直肠癌的方法。 根据组合物或试剂盒和方法，可以简单地诊断结肠直肠癌对结肠直肠癌具有高诊断准确性和特异性。

公开(公告)号：US20240115515A1

公开(公告)日：2024-04-11

申请号：US18166782

申请日：2023-02-09

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Dae-Ro AHN ,  Kyoung-Ran KIM ,  Junghyun KIM ,  Ji Eun LEE ,  Ji hyun BACK

IPC: A61K9/51 ,  A61K47/54 ,  A61P1/16 ,  C12N15/113

CPC classification number: A61K9/5169 ,  A61K47/549 ,  A61P1/16 ,  C12N15/113

Abstract: The present invention relates to a liver-specific drug delivery carrier comprising a nucleic acid nanoparticle and cholesterol; a liver-specific complex; a pharmaceutical composition for prevention or treatment of liver disease using the same; and a method for preventing or treating liver disease.

公开(公告)号：US20160054335A1

公开(公告)日：2016-02-25

申请号：US14779898

申请日：2014-03-25

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Cheolju LEE ,  Ji Eun LEE ,  Hye Jung KIM ,  Se Joon WOO ,  Jeeyun AHN ,  Kyu Hyung PARK ,  Eui Jin SUH

IPC: G01N33/68 ,  C07K16/18 ,  G01N33/50

CPC classification number: G01N33/6887 ,  C07K16/18 ,  C07K2317/21 ,  G01N33/5023 ,  G01N33/6848 ,  G01N33/6893 ,  G01N2333/4712 ,  G01N2500/00 ,  G01N2800/164 ,  G01N2800/7042

Abstract: A biomarker for diagnosing age-related macular degeneration includes a vinculin protein, and a diagnostic kit, a diagnostic method, and a method of screening a therapeutic material for age-related macular degeneration use the biomarker. The diagnostic kit and the diagnostic method of age-related macular degeneration are novel immunological diagnostic tools using the plasma of a patient, and have remarkable sensitivity that enables simple analysis of plasma without a biopsy, and thus can be useful for diagnosing age-related macular degeneration.

Abstract translation: 用于诊断年龄相关性黄斑变性的生物标志物包括纽蛋白蛋白，诊断试剂盒，诊断方法和筛选年龄相关性黄斑变性治疗材料的方法使用生物标志物。 诊断试剂盒和年龄相关性黄斑变性的诊断方法是使用患者血浆的新型免疫诊断工具，具有显着的灵敏度，能够在没有活检的情况下简单分析血浆，因此可用于诊断年龄相关性黄斑 退化。