公开(公告)号：US10913942B2

公开(公告)日：2021-02-09

申请号：US16204020

申请日：2018-11-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sun Mi Lee ,  Sangdo Yook ,  Youngsoon Um ,  Gyeongtaek Gong ,  Jiwon Kim

IPC: C12N9/92 ,  C12N1/16 ,  C12P7/64 ,  C12N9/12 ,  C12N15/01 ,  C12N15/52 ,  C07K14/39

Abstract: Disclosed herein are a yeast strain capable of utilizing xylose as a carbon source and a method for producing lipids using the same. The yeast strain is obtained by adaptively evolving a wild-type yeast strain which cannot utilize xylose as a carbon source so that it can produce high density lipids and then transforming the adaptively evolved strain to obtain the ability to metabolize xylose. Since the strain does not have the xylose metabolic pathway based on oxidoreductase, it can produce biodiesel and biomaterials based on lipid and lignocellulosic biomass at a high yield without a problem of cofactor imbalance and can greatly improve the economic feasibility and sustainability of the production processes of biodiesel and biomaterials.