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公开(公告)号：US10520514B2
公开(公告)日：2019-12-31
申请号：US15696302
申请日：2017-09-06
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Soo-Hyun Lee , Ji-Yoon Kang , Min-Ho Kim , Yun-Kyung Kim
IPC: G01N33/68 , G01N27/02 , G01N21/64 , G01N33/543 , G01N21/76
Abstract: According to a method for monitoring post-translational modifications of protein is provided, a first microbead by binding a protein antibody to a base bead is provided. A second microbead by binding a target protein having a first post-translational modification or a second post-translational modification, which are inversely proportional to each other, to the protein antibody of the first microbead, is provided. A third microbead by binding the second microbead to a first post-translational modification antibody is provided. A fourth microbead by binding the second microbead to a second post-translational modification antibody is provided. Impedances of the third and fourth microbeads are measured. A ratio of a first difference, between the impedances of the third microbead and a reference impedance, to a second difference, between the impedances of the fourth microbead and the reference impedance, is obtained.
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公开(公告)号：US20130098170A1
公开(公告)日：2013-04-25
申请号：US13644017
申请日：2012-10-03
Applicant: Korea Institute of Science and Technology
Inventor： Soo-Hyun Lee , Ji-Yoon Kang , Chang-Kun Park , Byung-Joo Kang
CPC classification number: G01L9/007
Abstract: Provided are a biocompatible pressure sensor which can be implanted into a body to wirelessly measure an internal pressure of the body outside the body, and a method of manufacturing the biocompatible pressure sensor. The biocompatible pressure sensor includes a coil inductor, a capacitor electrically connected with the coil inductor to constitute an LC resonant circuit together with the coil inductor, a flexible membrane disposed while being spaced apart from the coil inductor with an internal space interposed therebetween and surrounded by a housing, and a pressure displacement member fixed to one surface of the flexible membrane facing the coil inductor. The flexible membrane is transformed by external pressure to change a distance between the coil inductor and the pressure displacement member.
Abstract translation: 提供一种生物相容性压力传感器，其可以植入身体以无线地测量身体外部的身体的内部压力，以及制造生物相容性压力传感器的方法。 生物相容性压力传感器包括线圈电感器，与线圈电感器电连接以与线圈电感器一起构成LC谐振电路的电容器，与线圈电感器间隔开的柔性膜，其间插入有内部空间并被 壳体和固定到柔性膜的面向线圈电感器的一个表面的压力位移构件。 柔性膜通过外部压力变换以改变线圈电感器和压力位移构件之间的距离。
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公开(公告)号：US09341530B2
公开(公告)日：2016-05-17
申请号：US13644017
申请日：2012-10-03
Applicant: Korea Institute of Science and Technology
Inventor： Soo-Hyun Lee , Ji-Yoon Kang , Chang-Kun Park , Byung-Joo Kang
CPC classification number: G01L9/007
Abstract: Provided are a biocompatible pressure sensor which can be implanted into a body to wirelessly measure an internal pressure of the body outside the body, and a method of manufacturing the biocompatible pressure sensor. The biocompatible pressure sensor includes a coil inductor, a capacitor electrically connected with the coil inductor to constitute an LC resonant circuit together with the coil inductor, a flexible membrane disposed while being spaced apart from the coil inductor with an internal space interposed therebetween and surrounded by a housing, and a pressure displacement member fixed to one surface of the flexible membrane facing the coil inductor. The flexible membrane is transformed by external pressure to change a distance between the coil inductor and the pressure displacement member.
Abstract translation: 提供一种生物相容性压力传感器，其可以植入身体以无线地测量身体外部的身体的内部压力，以及制造生物相容性压力传感器的方法。 生物相容性压力传感器包括线圈电感器，与线圈电感器电连接以与线圈电感器一起构成LC谐振电路的电容器，与线圈电感器间隔开的柔性膜，其间插入有内部空间并被 壳体和固定到柔性膜的面向线圈电感器的一个表面的压力位移构件。 柔性膜通过外部压力变换以改变线圈电感器和压力位移构件之间的距离。
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