Composition for clearing of biotissue and clarity method for biotissue using thereof

    公开(公告)号:US10359344B2

    公开(公告)日:2019-07-23

    申请号:US15622529

    申请日:2017-06-14

    Abstract: The present invention relates to a composition for clearing biotissue and a clarity method for biotissue using the same. The composition for clearing biotissue and the clarity method for biotissue using the same of the present invention do not need a high price electrophoresis apparatus and expensive solutions, and can not only be applied to various biotissues including brain, liver, lung, kidney, intestine, heart, muscle, and blood vessel, without damaging any of them but also prevent bubble formation, color change, and dark sediment; improve the clarity of biotissues; and help antibody-staining of the cleared tissues. Therefore, it is useful to identify the reason of various diseases through structural imaging of biotissue and to establish a treatment method.

    COMPOSITION FOR CLEARING OF BIOTISSUE AND CLARITY METHOD FOR BIOTISSUE USING THEREOF

    公开(公告)号:US20180306687A1

    公开(公告)日:2018-10-25

    申请号:US15622529

    申请日:2017-06-14

    CPC classification number: G01N1/30 C07J41/0061 G01N1/34 G01N2001/305

    Abstract: The present invention relates to a composition for clearing biotissue and a clarity method for biotissue using the same. The composition for clearing biotissue and the clarity method for biotissue using the same of the present invention do not need a high price electrophoresis apparatus and expensive solutions, and can not only be applied to various biotissues including brain, liver, lung, kidney, intestine, heart, muscle, and blood vessel, without damaging any of them but also prevent bubble formation, color change, and dark sediment; improve the clarity of biotissues; and help antibody-staining of the cleared tissues. Therefore, it is useful to identify the reason of various diseases through structural imaging of biotissue and to establish a treatment method.

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