公开(公告)号：US20230047199A1

公开(公告)日：2023-02-16

申请号：US17903787

申请日：2022-09-06

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jae Ryung OH ,  Jae Ho HAN ,  Yeon Woo JEONG ,  Bo Ram LEE

IPC: G06T7/00 ,  A61B5/103

Abstract: Provided are apparatus and method for predicting biometrics using a fundus image. The method for predicting biometrics using a fundus image includes steps of preparation of a plurality of learning fundus images, generation of a learning model for predicting corresponding biometrics using the prepared data based on at least one characteristic of the fundus reflected in the prepared plurality of learning fundus images, reception of a prediction target of fundus image, and prediction of the biometrics of the subject of the prediction target of fundus image by using the generated learning model.

公开(公告)号：US20200181204A1

公开(公告)日：2020-06-11

申请号：US16663651

申请日：2019-10-25

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Jeewon LEE ,  Bo Ram LEE

IPC: C07K14/005 ,  C07K16/18 ,  C12N7/00 ,  A61K49/00 ,  A61K9/51

Abstract: The present invention relates to recombinant self-assembling protein nanoparticles presenting an albumin-binding peptide at the surface. For the recombinant self-assembling protein nanoparticles according to the present invention, an albumin-binding peptide can reduce the immunogenicity of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide is presented at the surface, and thus binds to an albumin protein present in vivo, and the albumin-binding peptide can also provide the cancer delivery function of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide binds to albumin around cancer. Simultaneously, the binding of the albumin-binding peptide to albumin can significantly increase the in vivo residence time of the recombinant self-assembling protein nanoparticles, thus increasing the potential for use in various medical applications.