公开(公告)号：US20170087200A1

公开(公告)日：2017-03-30

申请号：US15226255

申请日：2016-08-02

Applicant: KUWAIT UNIVERSITY

Inventor： Abdel-Majeed Safer

IPC: A61K36/82 ,  A61K9/00 ,  A61K9/50

CPC classification number: A61K36/82 ,  A61K9/0053 ,  A61K9/5036 ,  A61K9/5161

Abstract: The green tea extract composition for hepatic fibrosis includes green tea extract encapsulated in chitosan nanoparticles. In order to treat a patient suffering from hepatic fibrosis, the patient is administered a therapeutically effective dose of the green tea extract composition for hepatic fibrosis. The treatment is preferably administered orally. In order to make the green tea extract treatment, chitosan and green tea extract (prepared from Camellia sinensis) are mixed in de-ionized water to form a first solution, which is then stirred. Pentasodium triphosphate is added to the first solution to foam a second solution, which is then sonicated to form nanoparticles of green tea extract encapsulated in chitosan. Preferably, the second solution is further stirred for approximately two hours following the sonication.