公开(公告)号：US20040136967A1

公开(公告)日：2004-07-15

申请号：US10647361

申请日：2003-08-25

Applicant: Kansas State University Research Foundation

Inventor： Mark L. Weiss ,  Deryl L. Troyer ,  Duane Davis ,  Kathy E. Mitchell

IPC: C12N005/08

CPC classification number: C12N5/0619 ,  A61K35/12 ,  A61K48/00 ,  C12N5/0605 ,  C12N2500/25 ,  C12N2500/38 ,  C12N2500/62 ,  C12N2501/135 ,  C12N2506/1369

Abstract: Stem cells from human sources can have a variety of useful applications in disease treatment and biotechnology. More particularly the umbilical cord matrix cell cultures of the invention have a variety of totipotent, pluripotent, or multipotent cells for a variety of end uses from a non-controversial, universally available, species-specific source. The technology can have application to any amniotic animal, including agricultural and laboratory animals and humans. The invention relates to isolating the stem cells, culturing the stem cells, maintaining the stem cells, transforming the stem cells into useful cell types using genetic or other transformation technologies, stem cell and tissue banking and using untransformed or transformed cells in disease treatment.

Abstract translation: 来自人源的干细胞可以在疾病治疗和生物技术中具有多种有用的应用。 更具体地，本发明的脐带基质细胞培养物具有各种全能，多能或多能细胞，用于从无争议的，普遍可用的物种特异性来源的各种最终用途。 该技术可以应用于任何羊膜动物，包括农业和实验动物和人类。 本发明涉及分离干细胞，培养干细胞，保持干细胞，使用遗传或其它转化技术将干细胞转化为有用的细胞类型，干细胞和组织库，以及在疾病治疗中使用未转化或转化的细胞。

公开(公告)号：US20030161818A1

公开(公告)日：2003-08-28

申请号：US10083779

申请日：2002-02-25

Applicant: Kansas State University Research Foundation

Inventor： Mark L. Weiss ,  Deryl L. Troyer ,  Duane Davis ,  Kathy E. Mitchell

IPC: A61K048/00 ,  C12N005/08

CPC classification number: C12N5/0607 ,  A61K35/12 ,  A61K48/00

Abstract: Stem cells from human sources can have a variety of useful applications in disease treatment and biotechnology. More particularly the umbilical cord matrix stem (UCMS) cell cultures of the invention have a variety of totipotent, pluriotent, or multipotent cells for a variety of end uses from a non-controversial, universally available, species-specific source. The technology can have application to any placental animal, including agricultural and laboratory animals and humans. The invention relates to isolating, culturing the stem cells, maintaining the stem cells, transforming the stem cells into useful cell types using genetic or other transformation technologies, stem cell and tissue banking and using untransformed or transformed cells in disease treatment.

Abstract translation: 来自人源的干细胞可以在疾病治疗和生物技术中具有多种有用的应用。 更具体地，本发明的脐带基质干细胞（UCMS）细胞培养物具有多种全能，多产或多能细胞，用于从无争议的，普遍可用的物种特异性来源的多种最终用途。 该技术可以应用于任何胎盘动物，包括农业和实验动物和人类。 本发明涉及分离，培养干细胞，保持干细胞，使用遗传或其他转化技术，干细胞和组织库，以及在疾病治疗中使用未转化或转化的细胞将干细胞转化为有用的细胞类型。