-
公开(公告)号:US20120034242A1
公开(公告)日:2012-02-09
申请号:US13180644
申请日:2011-07-12
申请人: Karin Jooss , Jennifer Creson , Betty Li , Rodney Prell , Sandra Aung , Marina Boris Moskalenko , Thomas Du
发明人: Karin Jooss , Jennifer Creson , Betty Li , Rodney Prell , Sandra Aung , Marina Boris Moskalenko , Thomas Du
IPC分类号: A61K39/395 , A61P37/04 , A61P35/00 , A61K39/00 , A61K41/00
CPC分类号: A61K39/0011 , A61K38/193 , A61K38/2013 , A61K38/212 , A61K2039/505 , A61K2039/5156 , A61K2039/5158 , C07K16/2818 , C07K16/2878 , A61K2300/00
摘要: The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a cytokine-expressing cellular vaccine and at least one additional cancer therapeutic agent or treatment to a patient with cancer, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cellular vaccine or cancer therapeutic agent or treatment as a monotherapy.
摘要翻译: 本发明在其所有相关方面提供了用于治疗哺乳动物癌症的改进的方法和组合物,其基于将表达细胞因子的细胞疫苗和至少一种另外的癌症治疗剂或治疗组合给予癌症患者, 其中所述组合的给药相对于表达细胞因子的细胞疫苗或癌症治疗剂的施用或作为单一疗法的治疗而导致增强的治疗功效。
-
公开(公告)号:US20050002916A1
公开(公告)日:2005-01-06
申请号:US10807449
申请日:2004-03-24
申请人: Karin Jooss , Jennifer Creson , Betty Li , Rodney Prell , Sandra Aung , Marina Moskalenko , Thomas Du
发明人: Karin Jooss , Jennifer Creson , Betty Li , Rodney Prell , Sandra Aung , Marina Moskalenko , Thomas Du
IPC分类号: A61K38/19 , A61K38/20 , A61K38/21 , A61K39/00 , C07K16/28 , A61K48/00 , A61K31/337 , A61K31/704 , A61K39/395
CPC分类号: A61K39/0011 , A61K38/193 , A61K38/2013 , A61K38/212 , A61K2039/505 , A61K2039/5156 , A61K2039/5158 , C07K16/2818 , C07K16/2878 , A61K2300/00
摘要: The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a cytokine-expressing cellular vaccine and at least one additional cancer therapeutic agent or treatment to a patient with cancer, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cellular vaccine or cancer therapeutic agent or treatment as a monotherapy.
摘要翻译: 本发明在其所有相关方面提供了用于治疗哺乳动物癌症的改进的方法和组合物,其基于将表达细胞因子的细胞疫苗和至少一种另外的癌症治疗剂或治疗组合给予癌症患者, 其中所述组合的给药相对于表达细胞因子的细胞疫苗或癌症治疗剂的施用或作为单一疗法的治疗而导致增强的治疗功效。
-