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公开(公告)号:US20080268495A1
公开(公告)日:2008-10-30
申请号:US11996545
申请日:2006-08-27
申请人: Karl Skold , Marcus Svensson , Goran Palmers , Per E. Andren
发明人: Karl Skold , Marcus Svensson , Goran Palmers , Per E. Andren
CPC分类号: G01N1/44 , B01J2219/00051 , B01L7/00 , B01L2300/0832 , B01L2300/1805 , B01L2300/1838 , B01L2300/1866 , B01L2300/1883 , C07K14/435 , G01N1/286 , G01N33/68 , Y10T436/143333 , Y10T436/25
摘要: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
摘要翻译: 描述了用于制备用于分析的生物样品的方法和装置。 来自生物体的生物样品具有至少大分子,其具有在从生物体除去样品后自然降解的一级结构。 该方法包括使生物样品采用允许快速均匀加热的形状。 然后将成形的样品快速均匀地加热,从而改变大分子的二级结构,同时保持其主要结构。