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1.发明授权Pharmaceutical spray composition comprising a vitamin D analogue and a corticosteroid 有权包含维生素D类似物和皮质类固醇的药物喷雾组合物公开(公告)号：US09119781B2
公开(公告)日：2015-09-01
申请号：US13703214
申请日：2011-06-10
Applicant: Marianne Lind , Gritt Rasmussen , Mette Rydahl Sonne , Jens Hansen , Karsten Petersson
Inventor： Marianne Lind , Gritt Rasmussen , Mette Rydahl Sonne , Jens Hansen , Karsten Petersson
IPC: A61K9/12 , A61K9/00 , A61K31/573 , A61K31/58 , A61K31/593 , A61M35/00
CPC classification number: A61K31/593 , A61K9/0014 , A61K9/122 , A61K9/124 , A61K31/573 , A61K31/58 , A61K31/59 , A61K47/06 , A61K47/08 , A61K47/14 , A61K47/22 , A61M11/00 , A61M35/003 , A61M2210/04 , B65D83/207 , B65D83/752 , A61K2300/00
Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative and a corticosteroid, and its use in the treatment of dermal diseases and conditions. The spray comprises especially a propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethyl ether or a mixture thereof and further a pharmaceutically acceptable lipid carrier solubilised or suspended in said propellant.
Abstract translation: 本发明涉及包含生物活性维生素D衍生物和皮质类固醇的局部喷雾组合物及其在治疗真皮疾病和病症中的用途。 喷雾剂特别包括选自二甲醚，二乙醚和甲基乙基醚或其混合物的推进剂，以及溶解或悬浮在所述推进剂中的药学上可接受的脂质载体。
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2.发明申请PHARMACEUTICAL COMPOSITION COMPRISING SOLVENT MIXTURE AND A VITAMIN D DERIVATIVE OR ANALOGUE 审中-公开包含溶剂混合物和维生素D衍生物或模拟物的药物组合物公开(公告)号：US20130023501A1
公开(公告)日：2013-01-24
申请号：US13518314
申请日：2010-12-22
Applicant: Karsten Petersson
Inventor： Karsten Petersson
IPC: A61K31/593 , A61P17/06 , A61P17/10 , A61P17/00
CPC classification number: A61K31/593 , A61K9/0014 , A61K9/06 , A61K47/10 , A61K47/14 , A61K47/22
Abstract: A substantially anhydrous, topical pharmaceutical composition comprising a non-alcoholic three-component solvent mixture and a biologically active vitamin D derivative or analogue dissolved therein as well as a pharmaceutically acceptable carrier may be used in the treatment of dermal conditions.
Abstract translation: 可以使用包含非酒精三组分溶剂混合物和溶解于其中的生物活性维生素D衍生物或类似物以及药学上可接受的载体的基本上无水的局部药物组合物来治疗皮肤病症。
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3.发明申请PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID 有权包含维生素D类似物和角质层的药物喷雾组合物公开(公告)号：US20130123720A1
公开(公告)日：2013-05-16
申请号：US13703214
申请日：2011-06-10
Applicant: Marianne Lind , Gritt Rasmussen , Mette Rydahl Sonne , Jens Hansen , Karsten Petersson
Inventor： Marianne Lind , Gritt Rasmussen , Mette Rydahl Sonne , Jens Hansen , Karsten Petersson
CPC classification number: A61K31/593 , A61K9/0014 , A61K9/122 , A61K9/124 , A61K31/573 , A61K31/58 , A61K31/59 , A61K47/06 , A61K47/08 , A61K47/14 , A61K47/22 , A61M11/00 , A61M35/003 , A61M2210/04 , B65D83/207 , B65D83/752 , A61K2300/00
Abstract: The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative and a corticosteroid, and its use in the treatment of dermal diseases and conditions. The spray comprises especially a propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethyl ether or a mixture thereof and further a pharmaceutically acceptable lipid carrier solubilised or suspended in said propellant.
Abstract translation: 本发明涉及包含生物活性维生素D衍生物和皮质类固醇的局部喷雾组合物及其在治疗真皮疾病和病症中的用途。 喷雾剂特别包括选自二甲醚，二乙醚和甲基乙基醚或其混合物的推进剂，以及溶解或悬浮在所述推进剂中的药学上可接受的脂质载体。
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Patent Agency Ranking
4.发明申请CUTANEOUS COMPOSITION COMPRISING VITAMIN D ANALOGUE AND A MIXTURE OF SOLVENT AND SURFACTANTS 审中-公开包含维生素D类似物的固体组合物和溶剂和表面活性剂的混合物公开(公告)号：US20120322776A1
公开(公告)日：2012-12-20
申请号：US13518320
申请日：2010-12-22
Applicant: Karsten Petersson
Inventor： Karsten Petersson
CPC classification number: A61K31/592 , A61K9/0014 , A61K9/1075 , A61K31/593 , A61K47/06 , A61K47/14 , A61K47/18 , A61K47/44
Abstract: A pharmaceutical composition comprising a vitamin D derivative or analogue as the active ingredient dissolved in a three-component surfactant-solvent mixture is useful in the treatment of dermal disorders or conditions.
Abstract translation: 包含溶解在三组分表面活性剂 - 溶剂混合物中的作为活性成分的维生素D衍生物或类似物的药物组合物可用于治疗真皮病症或病症。
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5.发明授权Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture 有权包含维生素D类似物和助溶剂 - 表面活性剂混合物的药物组合物公开(公告)号：US09254296B2
公开(公告)日：2016-02-09
申请号：US13518333
申请日：2009-12-22
Applicant: Karsten Petersson
Inventor： Karsten Petersson
IPC: A61K31/593 , A61K31/592 , A61K31/7016 , A61P17/00 , A61P17/06 , A61P17/08 , A61P17/10 , A61K45/06 , A61K9/00 , A61K47/10 , A61K47/14 , A61K47/26 , A61K9/113 , A61K47/44
CPC classification number: A61K31/592 , A61K9/0014 , A61K9/113 , A61K31/593 , A61K31/7016 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44 , A61K2300/00
Abstract: A topical pharmaceutical composition which is an oil-in-water-oil emulsion comprising a vitamin D derivative or analogue dissolved in a mixture of a non-ionic surfactant and a lower alkanol. The topical pharmaceutical composition may be used in the treatment of dermal conditions, such as psoriasis.
Abstract translation: 一种局部药物组合物，其是包含溶解在非离子表面活性剂和低级链烷醇的混合物中的维生素D衍生物或类似物的水包油乳液。 局部药物组合物可用于治疗皮肤状况，如牛皮癣。
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6.发明申请COMPOSITION COMPRISING LIPID NANOPARTICLES AND A CORTICOSTEROID OR VITAMIN D DERIVATIVE 审中-公开包含脂质纳米颗粒和角质层或维生素D衍生物的组合物公开(公告)号：US20140079785A1
公开(公告)日：2014-03-20
申请号：US14006890
申请日：2012-03-23
Applicant: Louise Bastholm Jensen , Karsten Petersson
Inventor： Louise Bastholm Jensen , Karsten Petersson
IPC: A61K31/593 , A61K31/573
CPC classification number: A61K31/593 , A61K9/0014 , A61K9/5123 , A61K31/573 , A61K45/06 , A61K2300/00
Abstract: A pharmaceutical composition comprises, as a therapeutically active ingredient, a corticosteroid and/or vitamin D derivative incorporated as a solid solution or dispersion in lipid nanoparticles, said lipid nanoparticles being solid at ambient temperature and comprising a first lipid with a melting point above body temperature, the first lipid being a wax selected from the group consisting of esters of C12-24 alcohols and C12-24 fatty acids, glyceryl mono-, di- or triesters of C12-24 fatty acids, C12-24 fatty alcohols, and cholesterol, optionally a second lipid which is an oil at ambient temperature and miscible with the first lipid, and a pharmaceutically acceptable surfactant.
Abstract translation: 药物组合物包含作为治疗活性成分的作为固体溶液或分散体掺入脂质纳米颗粒中的皮质类固醇和/或维生素D衍生物，所述脂质纳米颗粒在环境温度下为固体，并且包含熔点高于体温的第一种脂质 第一种脂质是选自C12-24醇和C12-24脂肪酸的酯的蜡，C12-24脂肪酸的单 - ，二 - 或三酯，C12-24脂肪醇和胆固醇， 任选的第二脂质，其在环境温度下是油，并与第一种脂质混溶，和药学上可接受的表面活性剂。
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公开(公告)号：US20130039952A1
公开(公告)日：2013-02-14
申请号：US13518214
申请日：2010-12-22
Applicant: Karsten Petersson
Inventor： Karsten Petersson
IPC: A61K9/14 , A61P17/00 , A61P17/10 , C07C401/00 , A61K31/7016 , A61K31/593 , A61P17/06 , B82Y5/00
CPC classification number: A61K31/592 , A61K9/0014 , A61K9/06 , A61K9/146 , A61K31/593 , A61K45/06 , C07C35/21 , Y10T428/2982
Abstract: Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and conditions.
Abstract translation: 通过本文公开的方法制备的卡泊三醇一水合物纳米晶体可以掺入用于预防或治疗皮肤疾病和病症的药物组合物中。
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8.发明申请PHARMACEUTICAL COMPOSITION COMPRISING VITAMIN D ANALOGUE AND COSOLVENT-SURFACTANT MIXTURE 有权包含维生素D类似物和空气 - 表面活性剂混合物的药物组合物公开(公告)号：US20130005680A1
公开(公告)日：2013-01-03
申请号：US13518333
申请日：2009-12-22
Applicant: Karsten Petersson
Inventor： Karsten Petersson
IPC: A61K31/593 , A61K31/7016 , A61P17/10 , A61P17/06 , A61P17/08 , A61K31/592 , A61P17/00
CPC classification number: A61K31/592 , A61K9/0014 , A61K9/113 , A61K31/593 , A61K31/7016 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/44 , A61K2300/00
Abstract: A topical pharmaceutical composition which is an oil-in-water-oil emulsion comprising a vitamin D derivative or analogue dissolved in a mixture of a non-ionic surfactant and a lower alkanol. The topical pharmaceutical composition may be used in the treatment of dermal conditions, such as psoriasis.
Abstract translation: 一种局部药物组合物，其是包含溶解在非离子表面活性剂和低级链烷醇的混合物中的维生素D衍生物或类似物的水包油乳液。 局部药物组合物可用于治疗皮肤状况，如牛皮癣。
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