公开(公告)号：US5750470A

公开(公告)日：1998-05-12

申请号：US804916

申请日：1997-02-24

申请人： Katsushi Morimoto ,  Masatoshi Ohnari ,  Hiroyuki Furusawa ,  Takumi Terachi ,  Tsutomu Nawamaki ,  Kimihiro Ishikawa ,  Kunimitsu Nakahira ,  Chiaki Kawaguchi

发明人： Katsushi Morimoto ,  Masatoshi Ohnari ,  Hiroyuki Furusawa ,  Takumi Terachi ,  Tsutomu Nawamaki ,  Kimihiro Ishikawa ,  Kunimitsu Nakahira ,  Chiaki Kawaguchi

IPC分类号： A01N43/56 ,  A01N43/653 ,  A01N43/713 ,  A01N43/74 ,  A01N43/82 ,  C07D401/04 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04

CPC分类号： C07D401/04 ,  A01N43/56 ,  A01N43/653 ,  A01N43/713 ,  A01N43/74 ,  A01N43/82 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04

摘要： Provided are a pyridine derivative represented by the formula (1): ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 each independently represent a hydrogen atom, a C.sub.1-6 alkyl group, a C.sub.1-4 haloalkyl group, a C.sub.1-4 alkoxy group, a cyano group, a nitro group or a halogen atom, Qa represents a phenyl, pyrazolyl or pyridyl which may be substituted, Qb represents an azole, and X represents oxygen, sulfur or N-R.sup.4, R.sup.4 represents hydrogen or an alkyl group, and an agricultural chemical containing the same, particularly a herbicide.

摘要翻译： 提供由式（1）表示的吡啶衍生物：其中R1，R2和R3各自独立地表示氢原子，C1-6烷基，C1-4卤代烷基，C1-4 烷氧基，氰基，硝基或卤素原子，Qa表示可被取代的苯基，吡唑基或吡啶基，Qb表示唑，X表示氧，硫或N-R4，R4表示氢或烷基 和含有该农药的农药，特别是除草剂。

公开(公告)号：US5545608A

公开(公告)日：1996-08-13

申请号：US211988

申请日：1994-04-25

申请人： Katsushi Morimoto ,  Masatoshi Ohnari ,  Tsutomu Nawamaki ,  Shigeomi Watanabe ,  Kimihiro Ishikawa

发明人： Katsushi Morimoto ,  Masatoshi Ohnari ,  Tsutomu Nawamaki ,  Shigeomi Watanabe ,  Kimihiro Ishikawa

IPC分类号： A01N43/56 ,  A01P13/00 ,  C07D231/20 ,  C07D231/22 ,  C07D401/04 ,  C07D401/12 ,  C07D403/12 ,  C07D413/12

CPC分类号： C07D401/04 ,  C07D231/20 ,  C07D231/22 ,  C07D401/12 ,  C07D403/12 ,  C07D413/10

摘要： Pyrazole-glycolic acid amides of the following formula (1) (in which R.sup.1 to R.sup.5 each represent a hydrogen atom or a substituent having a broad definition), and herbicides containing them. The compounds have a high herbicidal effect against paddy weeds, especially Echinochloa crus-galli, while highly safe for paddy rice plants. ##STR1##

摘要翻译： PCT No.PCT / JP92 / 01476 Sec。 371日期1994年04月25日 102（e）日期1994年4月25日PCT提交1992年11月12日PCT公布。 WO93 / 10099 PCT出版物 日期1993年5月27日下式（1）（其中R 1至R 5各自表示氢原子或具有宽泛定义的取代基）的吡唑 - 乙醇酸酰胺和含有它们的除草剂。 这些化合物对稻田杂草尤其是稗草具有很高的除草效果，而对水稻植物则具有很高的安全性。 （1）

公开(公告)号：US20100029951A1

公开(公告)日：2010-02-04

申请号：US12588251

申请日：2009-10-08

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07D213/84 ,  C07C255/18

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

公开(公告)号：US20060178523A1

公开(公告)日：2006-08-10

申请号：US10551041

申请日：2004-03-26

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07C255/18

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

摘要翻译： 提供了一种用于立体选择性地生产3-酰氧基丙烯腈化合物（3）或Z-型的E-型的方法，其包括使3-氧代丙腈化合物（1）与酰氯（2）反应，其特征在于反应进行除去 的氯化氢，或通过使用有机碱或无机碱，从而调节产物的立体结构; 一种制备化合物（1）的方法，其特征在于在烃溶剂中使用碱金属醇盐使乙腈化合物（5）与芳族酯化合物（6）反应，同时通过共沸蒸馏除去形成副产物的醇 分离罐 以及通过使用有机碱将E-型3-酰氧基丙烯腈化合物异构化为Z-形式的方法。

公开(公告)号：US08324420B2

公开(公告)日：2012-12-04

申请号：US13137584

申请日：2011-08-26

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07C255/03

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

公开(公告)号：US08138368B2

公开(公告)日：2012-03-20

申请号：US12588251

申请日：2009-10-08

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07C255/03 ,  C07C211/78

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

摘要翻译： 提供了一种用于立体选择性地生产3-酰氧基丙烯腈化合物（3）或Z-型的E-型的方法，其包括使3-氧代丙腈化合物（1）与酰氯（2）反应，其特征在于反应进行除去 的氯化氢，或通过使用有机碱或无机碱，从而调节产物的立体结构; 一种制备化合物（1）的方法，其特征在于在烃溶剂中使用碱金属醇盐使乙腈化合物（5）与芳族酯化合物（6）反应，同时通过共沸蒸馏除去形成副产物的醇 分离罐 以及通过使用有机碱将E-型3-酰氧基丙烯腈化合物异构化为Z-形式的方法。

公开(公告)号：US20110313173A1

公开(公告)日：2011-12-22

申请号：US13137584

申请日：2011-08-26

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07D403/06 ,  C07D231/12

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

摘要翻译： 提供了一种用于立体选择性地生产3-酰氧基丙烯腈化合物（3）或Z-型的E-型的方法，其包括使3-氧代丙腈化合物（1）与酰氯（2）反应，其特征在于反应进行除去 的氯化氢，或通过使用有机碱或无机碱，从而调节产物的立体结构; 一种制备化合物（1）的方法，其特征在于在烃溶剂中使用碱金属醇盐使乙腈化合物（5）与芳族酯化合物（6）反应，同时通过共沸蒸馏除去形成副产物的醇 分离罐 以及通过使用有机碱将E-型3-酰氧基丙烯腈化合物异构化为Z-形式的方法。

公开(公告)号：US07649104B2

公开(公告)日：2010-01-19

申请号：US10551041

申请日：2004-03-26

申请人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

发明人： Kenzo Fukuda ,  Yasuo Kondo ,  Norio Tanaka ,  Hideaki Suzuki ,  Masatoshi Ohnari ,  Koichi Nishio

IPC分类号： C07C255/07

CPC分类号： C07D231/12

摘要： There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.

摘要翻译： 提供了一种用于立体选择性地生产3-酰氧基丙烯腈化合物（3）或Z-型的E-型的方法，其包括使3-氧代丙腈化合物（1）与酰氯（2）反应，其特征在于反应进行除去 的氯化氢，或通过使用有机碱或无机碱，从而调节产物的立体结构; 一种制备化合物（1）的方法，其特征在于在烃溶剂中使用碱金属醇盐使乙腈化合物（5）与芳族酯化合物（6）反应，同时通过共沸蒸馏除去形成副产物的醇 分离罐 以及通过使用有机碱将E-型3-酰氧基丙烯腈化合物异构化为Z-形式的方法。