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1.发明授权公开(公告)号：US08962832B2
公开(公告)日：2015-02-24
申请号：US13382988
申请日：2010-07-12
IPC分类号： C07D239/34
CPC分类号： C07D239/34
摘要： The invention relates to improved processes for the preparation of ambrisentan. The invention also relates to a novel intermediate useful in the preparation of ambrisentan and a process for the preparation of the intermediate. The invention also relates to new polymorphic form of ambrisentan. In particular, it relates to a polymorphic form, designated as Form I of ambrisentan and a process for the preparation of the Form I.
摘要翻译： 本发明涉及制备安立生坦的改进方法。 本发明还涉及可用于制备安立生坦的新型中间体及其制备方法。 本发明还涉及新的多晶型形式的安立生坦。 特别地，它涉及一种称为安立生坦形式I的多晶型物，以及形式I的制备方法。
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公开(公告)号：US20120184573A1
公开(公告)日：2012-07-19
申请号：US13382988
申请日：2010-07-12
IPC分类号： A61K31/505 , C07C213/08 , C07C217/58 , C07C209/68 , C07D239/34 , C07C211/29
CPC分类号： C07D239/34
摘要： The invention relates to improved processes for the preparation of ambrisentan. The invention also relates to a novel intermediate useful in the preparation of ambrisentan and a process for the preparation of the intermediate. The invention also relates to new polymorphic form of ambrisentan. In particular, it relates to a polymorphic form, designated as Form I of ambrisentan and a process for the preparation of the Form I.
摘要翻译： 本发明涉及制备安立生坦的改进方法。 本发明还涉及可用于制备安立生坦的新型中间体及其制备方法。 本发明还涉及新的多晶型形式的安立生坦。 特别地，它涉及一种称为安立生坦形式I的多晶型物，以及形式I的制备方法。
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