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    Processes for producing optically active 2-amino-1-phenylethanol derivatives
    3.
    发明授权
    Processes for producing optically active 2-amino-1-phenylethanol derivatives 失效
    光学活性2-氨基-1-苯基乙醇衍生物的制备方法

    公开(公告)号：US6114582A

    公开(公告)日：2000-09-05

    申请号：US095733

    申请日：1998-06-11

    申请人： Kazuaki Furukawa ,  Takayuki Abe ,  Hidekazu Akamatsu

    发明人： Kazuaki Furukawa ,  Takayuki Abe ,  Hidekazu Akamatsu

    IPC分类号： C07C213/00 ,  C07C213/04 ,  C07C213/08 ,  C07C213/10 ,  C07C215/08 ,  C07C231/18 ,  C12P7/22 ,  C12P13/00 ,  C12P41/00

    CPC分类号： C12P7/22 ,  C07C213/00 ,  C07C213/04 ,  C07C213/08 ,  C07C213/10 ,  C07C231/18 ,  C12P13/001 ,  C12P13/008 ,  C12P41/00 ,  C12P41/001 ,  C12P41/002 ,  Y10S435/822 ,  Y10S435/911

    摘要： An (R)-2-amino-1-phenylethanol derivative shown by the general formula (IIa) ##STR1## wherein R.sup.1 and R.sup.5 represent a hydrogen atom, etc.; R.sup.2, R.sup.3 and R.sup.4 independently represent a halogen atom, etc., or a salt thereof, can readily be produced (1) by permitting a Microorganism belonging to the genus Rhodosporidium, the genus Comamonas or the like to act on a mixture of corresponding (R)-form and (S)-form to asymmetrically utilize, or (2) by permitting a microorganism belonging to the genus Lodderomyces, the genus Pilimelia or the like to act on a corresponding aminoketone derivative to asymmetrically reduce. An (R,R)-1-phenyl-2-[(2-phenyl-1-alkylethyl) amino]ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (IIa) or a salt thereof. Said derivative is useful as an intermediate for producing an anti-obesity agent and so on.

    摘要翻译： 由通式（IIa）表示的（R）-2-氨基-1-苯基乙醇衍生物，其中R 1和R 5表示氢原子等; R2，R3和R4独立地表示卤素原子等，或其盐可容易地制备（1）通过使属于Rhodosporidium属，Comamonas属等的微生物作用于相应的（ 或者（2）通过允许属于罗德氏菌属的属微生物，类风云属等的微生物作用于相应的氨基酮衍生物以不对称地还原。 具有高光学纯度的（R，R）-1-苯基-2 - [（2-苯基-1-烷基乙基）氨基]乙醇衍生物可以容易地从式（IIa）化合物或其盐获得。 所述衍生物可用作生产抗肥胖剂等的中间体。

    Processes for producing optically active 2-amino-1-phenylethanol derivatives
    4.
    发明授权
    Processes for producing optically active 2-amino-1-phenylethanol derivatives 失效
    光学活性2-氨基-1-苯基乙醇衍生物的制备方法

    公开(公告)号：US06528686B1

    公开(公告)日：2003-03-04

    申请号：US09597830

    申请日：2000-06-19

    申请人： Hidekazu Akamatsu ,  Noritsugu Yamasaki

    发明人： Hidekazu Akamatsu ,  Noritsugu Yamasaki

    IPC分类号： C07C21504

    CPC分类号： C12P7/22 ,  C07C213/00 ,  C07C213/04 ,  C07C213/08 ,  C07C213/10 ,  C07C231/18 ,  C12P13/001 ,  C12P13/008 ,  C12P41/00 ,  C12P41/001 ,  C12P41/002 ,  Y10S435/822 ,  Y10S435/911 ,  C07C215/08

    摘要： An (R)-2-amino-1-phenylethanol derivative shown by the general formula (IIa) wherein R1 and R5 represent a hydrogen atom, etc.; R2, R3 and R4 independently represent a halogen atom, etc., or a salt thereof, can readily be produced (1) by permitting a microorganism belonging to the genus Rhodosporidium, the genus Comamonas or the like to act on a mixture of corresponding (R)-form and (S)-form to asymmetrically utilize, or (2) by permitting a microorganism belonging to the genus Lodderomyces, the genus Pilimelia or the like to act on a corresponding aminoketone derivative to asymmetrically reduce. An (R,R)-1-phenyl-2-[(2-phenyl-1-alkylethyl)amino]ethanol derivative having a high optical purity can easily be obtained from the compound of the formula (IIa) or a salt thereof. Said derivative is useful as an intermediate for producing an anti-obesity agent and so on.

    摘要翻译： 由通式（IIa）表示的（R）-2-氨基-1-苯基乙醇衍生物，其中R 1和R 5表示氢原子等; R2，R3和R4独立地表示卤素原子等，或其盐可以容易地制备（1）通过使属于Rhodosporidium属，Comamonas属等的微生物作用于相应的（ 或者（2）通过允许属于罗德氏菌属的属微生物，类风云属等的微生物作用于相应的氨基酮衍生物以不对称地还原。 具有高光学纯度的（R，R）-1-苯基-2 - [（2-苯基-1-烷基乙基）氨基]乙醇衍生物可以容易地从式（IIa）化合物或其盐获得。 所述衍生物可用作生产抗肥胖剂等的中间体。

    Thermal head and thermal printer provided with same
    5.
    发明授权
    Thermal head and thermal printer provided with same 有权
    配有相同的热敏头和热敏打印机

    公开(公告)号：US08922610B2

    公开(公告)日：2014-12-30

    申请号：US14128590

    申请日：2012-06-22

    申请人： Youichi Moto ,  Hidekazu Akamatsu ,  Daisaku Kato ,  Naoto Matsukubo ,  Akihiro Fukami ,  Kouhei Nakada

    发明人： Youichi Moto ,  Hidekazu Akamatsu ,  Daisaku Kato ,  Naoto Matsukubo ,  Akihiro Fukami ,  Kouhei Nakada

    IPC分类号： B41J2/335 ,  B41J2/345

    CPC分类号： B41J2/3351 ,  B41J2/3354 ,  B41J2/3357 ,  B41J2/345

    摘要： A thermal head and a thermal printer are disclosed. The head includes a substrate, heat generating members, an edge portion, and first and second reinforcing members. The substrate includes: first and second surfaces opposing to each other; and an end face connecting the first and second surfaces. The heat generating members are parallel to the end face and located on the substrate. The edge portion is located on the substrate, crosses an array direction of the heating generating members, and includes first, second and third edge portions on the first main surface, the second main surface and the first end face, respectively. The first reinforcing member is located on the first, second and third edge portions. The second reinforcing member is located on the first edge portion, and separated from the first reinforcing member.

    摘要翻译： 公开了一种热敏头和热敏打印机。 头包括衬底，发热构件，边缘部分以及第一和第二加强构件。 基板包括：彼此相对的第一和第二表面; 以及连接第一和第二表面的端面。 发热部件平行于端面并位于基板上。 所述边缘部分位于所述基板上，与所述加热发生部件的排列方向交叉，并且分别包括所述第一主表面，所述第二主表面和所述第一端面上的第一，第二和第三边缘部分。 第一加强构件位于第一，第二和第三边缘部分上。 第二加强构件位于第一边缘部分上并且与第一加强构件分离。

    THERMAL HEAD AND THERMAL PRINTER PROVIDED WITH SAME
    6.
    发明申请
    THERMAL HEAD AND THERMAL PRINTER PROVIDED WITH SAME 有权
    热头和热打印机

    公开(公告)号：US20140132696A1

    公开(公告)日：2014-05-15

    申请号：US14128590

    申请日：2012-06-22

    申请人： Youichi Moto ,  Hidekazu Akamatsu ,  Daisaku Kato ,  Naoto Matsukubo ,  Akihiro Fukami ,  Kouhei Nakada

    发明人： Youichi Moto ,  Hidekazu Akamatsu ,  Daisaku Kato ,  Naoto Matsukubo ,  Akihiro Fukami ,  Kouhei Nakada

    IPC分类号： B41J2/335

    CPC分类号： B41J2/3351 ,  B41J2/3354 ,  B41J2/3357 ,  B41J2/345

    摘要： A thermal head and a thermal printer are disclosed. The head includes a substrate, heat generating members, an edge portion, and first and second reinforcing members. The substrate includes: first and second surfaces opposing to each other; and an end face connecting the first and second surfaces. The heat generating members are parallel to the end face and located on the substrate. The edge portion is located on the substrate, crosses an array direction of the heating generating members, and includes first, second and third edge portions on the first main surface, the second main surface and the first end face, respectively. The first reinforcing member is located on the first, second and third edge portions. The second reinforcing member is located on the first edge portion, and separated from the first reinforcing member.

    摘要翻译： 公开了一种热敏头和热敏打印机。 头包括衬底，发热构件，边缘部分以及第一和第二加强构件。 基板包括：彼此相对的第一和第二表面; 以及连接第一和第二表面的端面。 发热部件平行于端面并位于基板上。 所述边缘部分位于所述基板上，与所述加热发生部件的排列方向交叉，并且分别包括所述第一主表面，所述第二主表面和所述第一端面上的第一，第二和第三边缘部分。 第一加强构件位于第一，第二和第三边缘部分上。 第二加强构件位于第一边缘部分上并且与第一加强构件分离。