公开(公告)号：US08518994B2

公开(公告)日：2013-08-27

申请号：US13140468

申请日：2009-12-25

申请人： Kazuaki Wakita ,  Susumu Tanaka ,  Kei-ichi Maruyama

发明人： Kazuaki Wakita ,  Susumu Tanaka ,  Kei-ichi Maruyama

IPC分类号： A61K8/44 ,  C07C279/14 ,  C07C277/08 ,  A61Q19/00

CPC分类号： C07C279/14 ,  A61K8/44 ,  A61Q19/00 ,  C07C277/08

摘要： An object of the invention is to provide a novel arginine derivative and a cosmetic satisfactory in compatibility with the skin and hair, excellent in skin softening effect and skin-conditioning effect, and satisfactory in use feeling with little sticky feeling and tense feeling.Such present invention relates to an arginine derivative represented by the following general formula (1): wherein R1 and R2 are a hydrogen atom or a linear or branched monohydroxyalkyl group having 2 to 3 carbon atoms and at least one of R1 and R2 represents a linear or branched monohydroxyalkyl group having 2 to 3 carbon atoms; and R3 represents a hydrogen atom, an alkali metal atom, an ammonium, or an organic ammonium, and a cosmetic containing the same mixed therein.

摘要翻译： 本发明的目的是提供一种新颖的精氨酸衍生物和与皮肤和头发的相容性令人满意的化妆品，具有优异的皮肤柔软效果和皮肤调理效果，并且使用感好，粘着感和紧张感少。 本发明涉及由以下通式（1）表示的精氨酸衍生物：其中R 1和R 2是氢原子或具有2至3个碳原子的直链或支链单羟基烷基，并且R 1和R 2中的至少一个表示直链 或具有2〜3个碳原子的支链单羟基烷基; 并且R 3表示氢原子，碱金属原子，铵或有机铵，以及含有它们的化妆品。

公开(公告)号：US20110245344A1

公开(公告)日：2011-10-06

申请号：US13140468

申请日：2009-12-25

申请人： Kazuaki Wakita ,  Susumu Tanaka ,  Kei-ichi Maruyama

发明人： Kazuaki Wakita ,  Susumu Tanaka ,  Kei-ichi Maruyama

IPC分类号： A61K8/44 ,  C07C279/14 ,  C07C277/08 ,  A61Q19/00

CPC分类号： C07C279/14 ,  A61K8/44 ,  A61Q19/00 ,  C07C277/08

摘要： An object of the invention is to provide a novel arginine derivative and a cosmetic satisfactory in compatibility with the skin and hair, excellent in skin softening effect and skin-conditioning effect, and satisfactory in use feeling with little sticky feeling and tense feeling.Such present invention relates to an arginine derivative represented by the following general formula (1): wherein R1 and R2 are a hydrogen atom or a linear or branched monohydroxyalkyl group having 2 to 3 carbon atoms and at least one of R1 and R2 represents a linear or branched monohydroxyalkyl group having 2 to 3 carbon atoms; and R3 represents a hydrogen atom, an alkali metal atom, an ammonium, or an organic ammonium, and a cosmetic containing the same mixed therein.

摘要翻译： 本发明的目的是提供一种新颖的精氨酸衍生物和与皮肤和头发的相容性令人满意的化妆品，具有优异的皮肤柔软效果和皮肤调理效果，并且使用感好，粘着感和紧张感少。 本发明涉及由以下通式（1）表示的精氨酸衍生物：其中R 1和R 2是氢原子或具有2至3个碳原子的直链或支链单羟基烷基，并且R 1和R 2中的至少一个表示直链 或具有2〜3个碳原子的支链单羟基烷基; 并且R 3表示氢原子，碱金属原子，铵或有机铵，以及含有它们的化妆品。

公开(公告)号：US08334397B2

公开(公告)日：2012-12-18

申请号：US12864737

申请日：2009-01-28

申请人： Kazuaki Wakita ,  Susumu Tanaka ,  Keiichi Maruyama

发明人： Kazuaki Wakita ,  Susumu Tanaka ,  Keiichi Maruyama

IPC分类号： C07C51/00

CPC分类号： C08G65/2615 ,  A23L27/86 ,  C08G65/30

摘要： A process for producing a polyoxyethylene sorbitan fatty acid ester in which the bitterness just after the production and the bitterness with the lapse of time is suppressed. The process of the invention includes reacting an ester (component A) of a fatty acid having 10 to 22 carbon atoms and a monohydric alcohol having 1 to 3 carbon atoms with at least either (component B) of sorbitol and sorbitan to form a sorbitan fatty acid ester and adding ethylene oxide to the sorbitan fatty acid ester, thereby producing a polyoxyethylene sorbitan fatty acid ester, which is characterized that the following steps (a) to (d) are contained: (a) the component B is provided in the form of a 50 to 90% by weight aqueous solution and mixed with the component A and dehydration was performed until a water content in the system reaches 1.0% by weight or less based on the total weight of the components A and B; (b) 1 to 10% by weight of a monohydric alcohol having 1 to 3 carbon atoms and 0.1 to 1.0% by weight of an alkali catalyst based on the total weight of the components A and B are added at 50 to 90° C.; (c) a transesterification reaction is performed under a nitrogen stream at a reaction temperature of 140 to 190° C. to thereby obtain a sorbitan fatty acid ester; (d) ethylene oxide is added thereto at a reaction temperature of 70 to 130° C.

摘要翻译： 制造聚合物脱水山梨糖醇脂肪酸酯的方法，其中刚刚生产后的苦味和经过了时间的苦味被抑制。 本发明的方法包括将具有10-22个碳原子的脂肪酸的酯（组分A）和具有1至3个碳原子的一元醇与山梨糖醇和脱水山梨糖醇中的至少一种（组分B）反应以形成脱水山梨糖醇脂肪 酸酐，并将环氧乙烷加入脱水山梨糖醇脂肪酸酯中，由此制备聚氧乙烯山梨糖醇酐脂肪酸酯，其特征在于包含以下步骤（a）至（d）：（a）组分B以 的50〜90重量％的水溶液并与组分A混合，并进行脱水，直到系统中的水含量基于组分A和B的总重量达到1.0重量％或更少; （b）在50至90℃下加入1至10重量％的具有1至3个碳原子的一元醇和0.1至1.0重量％的碱催化剂，基于组分A和B的总重量。 ; （c）在氮气流下，在140〜190℃的反应温度下进行酯交换反应，得到脱水山梨醇脂肪酸酯; （d）在70〜130℃的反应温度下加入环氧乙烷

公开(公告)号：US20100311996A1

公开(公告)日：2010-12-09

申请号：US12864737

申请日：2009-01-28

申请人： Kazuaki Wakita ,  Susumu Tanaka ,  Keiichi Maruyama

发明人： Kazuaki Wakita ,  Susumu Tanaka ,  Keiichi Maruyama

IPC分类号： C07C67/24

CPC分类号： C08G65/2615 ,  A23L27/86 ,  C08G65/30

摘要： An object of the present invention is to provide a process for producing a polyoxyethylene sorbitan fatty acid ester in which the bitterness just after the production is suppressed and also an increase in the bitterness with the lapse of time is suppressed.The process for producing a polyoxyethylene sorbitan fatty acid ester of the invention includes reacting an ester (component A) of a fatty acid having 10 to 22 carbon atoms and a monohydric alcohol having 1 to 3 carbon atoms with at least either (component B) of sorbitol and sorbitan to form a sorbitan fatty acid ester and adding ethylene oxide to the sorbitan fatty acid ester, thereby producing a polyoxyethylene sorbitan fatty acid ester, which is characterized that the following steps (a) to (d) are contained: (a) the component B is provided in the form of a 50 to 90% by weight aqueous solution and mixed with the component A and dehydration was performed until a water content in the system reaches 1.0% by weight or less based on the total weight of the components A and B; (b) 1 to 10% by weight of a monohydric alcohol having 1 to 3 carbon atoms and 0.1 to 1.0% by weight of an alkali catalyst based on the total weight of the components A and B are added at 50 to 90° C.; (c) a transesterification reaction is performed under a nitrogen stream at a reaction temperature of 140 to 190° C. to thereby obtain a sorbitan fatty acid ester; (d) ethylene oxide is added thereto at a reaction temperature of 70 to 130° C.

摘要翻译： 本发明的目的是提供一种制造聚合物脱水山梨糖醇脂肪酸酯的方法，其中抑制刚刚生产后的苦味，并且抑制了随着时间的流逝而引起的苦味的增加。 本发明的聚氧乙烯脱水山梨糖醇脂肪酸酯的制造方法包括将具有10〜22个碳原子的脂肪酸的酯（A成分）与碳原子数1〜3的一元醇与（B成分） 山梨糖醇酐和脱水山梨糖醇形成山梨糖醇酐脂肪酸酯，并向脱水山梨醇脂肪酸酯中加入环氧乙烷，由此制备聚氧乙烯山梨糖醇酐脂肪酸酯，其特征在于包含以下步骤（a）至（d）：（a） 组分B以50至90重量％的水溶液的形式提供并与组分A混合，并进行脱水，直到系统中的水含量基于组分的总重量达到1.0重量％或更少 A和B; （b）在50至90℃下加入1至10重量％的具有1至3个碳原子的一元醇和0.1至1.0重量％的碱催化剂，基于组分A和B的总重量。 ; （c）在氮气流下，在140〜190℃的反应温度下进行酯交换反应，得到脱水山梨醇脂肪酸酯; （d）在70〜130℃的反应温度下加入环氧乙烷

公开(公告)号：US20130165528A1

公开(公告)日：2013-06-27

申请号：US13822738

申请日：2011-09-12

申请人： Kazuaki Wakita ,  Satoko Matani

发明人： Kazuaki Wakita ,  Satoko Matani

IPC分类号： A01N25/30

CPC分类号： A01N25/30 ,  A01N37/12 ,  A01N43/08 ,  C11D1/667 ,  C11D1/72 ,  C11D1/825 ,  C11D3/48 ,  A01N2300/00 ,  A01N31/02

摘要： A disinfectant detergent composition containing a food or food additive as a main component is provided. The disinfectant detergent composition contains the following components (a), (b), and (c). The sum [a+b] of the component (a) content and the component (b) content of the composition ranges from 0.1% to 30% by mass, the mass ratio [a/b] of the component (a) to the component (b) ranges from 1/2 to 4/1, and the component (c) content of the composition ranges from 60% to 99.5% by mass. (a) polyoxyethylene sorbitan monolaurate (b) a fatty acid glyceride in which the number of carbon atoms of its acyl group ranges from 8 to 12, the monoglyceride content of the component (b) being 85% by mass or more, the mass fraction of 1-monoglyceride relative to the total amount of monoglycerides being in the range of 0.9 to 1.0 (c) water and/or ethanol.

摘要翻译： 提供含有食品添加剂或食品添加剂作为主要成分的消毒洗涤剂组合物。 消毒洗涤剂组合物含有下列成分（a），（b）和（c）。 组分（a）含量和组分（b）含量的总和[a + b]为0.1〜30质量％，成分（a）的质量比[a / b] 组分（b）的范围为1/2至4/1，组分（c）的组成范围为60-99.5质量％。 （a）聚氧乙烯山梨糖醇酐单月桂酸酯（b）其酰基碳原子数为8〜12的脂肪酸甘油酯，（b）成分的甘油单酯含量为85质量％以上，质量分数 的单甘油酯相对于单酸甘油酯的总量​​在0.9至1.0的范围内（c）水和/或乙醇。

公开(公告)号：US09288977B2

公开(公告)日：2016-03-22

申请号：US13822738

申请日：2011-09-12

申请人： Kazuaki Wakita ,  Satoko Matani

发明人： Kazuaki Wakita ,  Satoko Matani

IPC分类号： A01N25/30 ,  A01N37/12 ,  A01N43/08 ,  C11D1/825 ,  C11D3/48 ,  C11D1/66 ,  C11D1/72

CPC分类号： A01N25/30 ,  A01N37/12 ,  A01N43/08 ,  C11D1/667 ,  C11D1/72 ,  C11D1/825 ,  C11D3/48 ,  A01N2300/00 ,  A01N31/02

摘要： A disinfectant detergent composition containing a food or food additive as a main component is provided. The disinfectant detergent composition contains the following components (a), (b), and (c). The sum [a+b] of the component (a) content and the component (b) content of the composition ranges from 0.1% to 30% by mass, the mass ratio [a/b] of the component (a) to the component (b) ranges from 1/2 to 4/1, and the component (c) content of the composition ranges from 60% to 99.5% by mass. (a) polyoxyethylene sorbitan monolaurate (b) a fatty acid glyceride in which the number of carbon atoms of its acyl group ranges from 8 to 12, the monoglyceride content of the component (b) being 85% by mass or more, the mass fraction of 1-monoglyceride relative to the total amount of monoglycerides being in the range of 0.9 to 1.0 (c) water and/or ethanol.

摘要翻译： 提供含有食品添加剂或食品添加剂作为主要成分的消毒洗涤剂组合物。 消毒洗涤剂组合物含有下列成分（a），（b）和（c）。 组分（a）含量和组分（b）含量的总和[a + b]为0.1〜30质量％，成分（a）的质量比[a / b] 组分（b）的范围为1/2至4/1，组分（c）的组成范围为60-99.5质量％。 （a）聚氧乙烯山梨糖醇酐单月桂酸酯（b）其酰基碳原子数为8〜12的脂肪酸甘油酯，（b）成分的甘油单酯含量为85质量％以上，质量分数 的单甘油酯相对于单酸甘油酯的总量​​在0.9至1.0的范围内（c）水和/或乙醇。