Process for producing human lysozyme
    1.
    发明授权
    Process for producing human lysozyme 失效
    生产人溶菌酶的方法

    公开(公告)号:US4104125A

    公开(公告)日:1978-08-01

    申请号:US815359

    申请日:1977-07-13

    IPC分类号: A61K38/00 C12N9/36 C07G7/026

    摘要: It has been discovered that lysozyme in the blood is concentrated into the albumin fraction when the blood is fractionated by the alcohol fractionation method at lowered temperature or the ammonium sulfate fractionation method. Lysozyme can be produced by contacting the albumin fraction with a weakly acidic cation-exchanger such as CM-cellulose to adsorb selectively the lysozyme with the cation-exchanger and then eluting the lysozyme adsorbed from the cation-exchanger.

    摘要翻译: 已经发现,当血液在降低的温度下通过醇分馏法或硫酸铵分级法分离时,将血液中的溶菌酶浓缩成白蛋白部分。 可以通过使白蛋白部分与弱酸性阳离子交换剂如CM-纤维素接触来产生溶菌酶,以便用阳离子交换剂选择性地吸附溶菌酶,然后洗脱从阳离子交换器吸附的溶菌酶。