Mutant DNA polymerases with improved pyrophosphorolysis activated polymerization (PAP) ability
    1.
    发明授权
    Mutant DNA polymerases with improved pyrophosphorolysis activated polymerization (PAP) ability 有权
    突变型DNA聚合酶具有改善的焦磷酸裂解活化聚合(PAP)能力

    公开(公告)号:US08071536B2

    公开(公告)日:2011-12-06

    申请号:US12324491

    申请日:2008-11-26

    CPC分类号: C12N9/1252

    摘要: Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.

    摘要翻译: 公开了相对于相应的未修饰聚合酶具有改进的延伸速率的突变型DNA聚合酶。 突变型聚合酶可用于各种公开的引物延伸方法。 还公开了相关组合物,包括重组核酸,载体和宿主细胞,其可用于例如用于产生突变型DNA聚合酶。