公开(公告)号：US20060099246A1

公开(公告)日：2006-05-11

申请号：US10984205

申请日：2004-11-08

申请人： Keith Tanner ,  Rickey Shelley ,  Norman Stroud ,  Elizabeth Youngblood

发明人： Keith Tanner ,  Rickey Shelley ,  Norman Stroud ,  Elizabeth Youngblood

IPC分类号： A61K9/48

CPC分类号： A61K9/4816

摘要： A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.

公开(公告)号：US06884060B2

公开(公告)日：2005-04-26

申请号：US10016352

申请日：2001-11-02

申请人： Keith Tanner ,  Steve Burnett ,  David Walker ,  Peter Beke ,  Norman Stroud ,  Mani Sundararajan

发明人： Keith Tanner ,  Steve Burnett ,  David Walker ,  Peter Beke ,  Norman Stroud ,  Mani Sundararajan

IPC分类号： B29C47/14 ,  A61K9/48 ,  B29C47/50 ,  B29C47/54 ,  B29C47/88 ,  B29L7/00

CPC分类号： A61K9/4833 ,  A61K9/4816 ,  B29C47/0021 ,  B29C47/14 ,  B29C47/367 ,  B29C47/54 ,  B29C47/8845 ,  B29L2031/7164

摘要： This invention relates to a method and apparatus for forming soft capsules and provides novel processing flexibility. The apparatus includes extrusion dies as an alternative to spreader boxes and the use of melt-on-demand technology to enhance the long term stability of the film-forming materials. Preferred embodiments provide a positive displacement pump to transport the molten film-forming material from the melt-on-demand device to the extrusion device and preferably a reservoir means disposed between said extrusion device and said means to melt said film-forming material. The encapsulation apparatus may also include a valved injection wedge.

摘要翻译： 本发明涉及一种形成软胶囊的方法和装置，并且提供了新的加工灵活性。 该设备包括作为扩展箱的替代的挤出模具和使用熔融按需技术来增强成膜材料的长期稳定性。 优选的实施方案提供了一种容积式泵，用于将熔融成膜材料从熔融需求装置输送到挤出装置，优选地，设置在所述挤压装置和所述装置之间的储存装置，以熔化所述成膜材料。 封装装置还可以包括带阀的注入楔。

公开(公告)号：US5554385A

公开(公告)日：1996-09-10

申请号：US343185

申请日：1994-11-22

申请人： Norman Stroud

发明人： Norman Stroud

IPC分类号： A61K9/48

CPC分类号： A61K9/4816 ,  Y10S514/962

摘要： A gelatin capsule sheath in which a portion of the gelatin is replaced with a high amylose content starch to provide a dry capsule sheath having 3-60% by weight high amylose starch wherein the amylose content of the starch is at least 50% and preferably 90% high amylose starch. The capsules of this invention have textured frosted or satin finish which do not stick together, form strong seals, are resistant to changes in shape, and are more economical to manufacture.

摘要翻译： 明胶胶囊护套，其中一部分明胶被高直链淀粉含量的淀粉代替以提供具有3-60重量％高直链淀粉的干胶囊，其中淀粉的直链淀粉含量为至少50％，优选为90 ％高直链淀粉。 本发明的胶囊具有纹理磨砂或缎纹，其不粘在一起，形成强密封，抵抗形状变化，并且制造更加经济。