公开(公告)号：US5141847A

公开(公告)日：1992-08-25

申请号：US482231

申请日：1990-02-20

申请人： Keizo Sugimachi ,  Kenji Takenaka ,  Mitsuo Shimada ,  Kengo Fukuzawa ,  Takashi Nishizaki ,  Tetsuo Ikeda ,  Atsushi Yoshihara

发明人： Keizo Sugimachi ,  Kenji Takenaka ,  Mitsuo Shimada ,  Kengo Fukuzawa ,  Takashi Nishizaki ,  Tetsuo Ikeda ,  Atsushi Yoshihara

IPC分类号： A61M1/10 ,  A01N1/02 ,  A61M1/16 ,  A61M1/36

CPC分类号： A61M1/3621 ,  A01N1/02 ,  A01N1/0247 ,  A61M1/1005 ,  A61M1/1698 ,  A61M2205/3337 ,  Y10T137/86405 ,  Y10T137/86421

摘要： In an apparatus which applies periodic pulsation to a solution flowing through a conduit while undergoing perfusion by a pump, a first valve is disposed in the conduit downstream of the pump, a bypass line is provided to the conduit downstream of the first valve, and a second valve is disposed in the bypass line for withdrawing some of a first pulsed flow formed in the conduit by opening and closing the first valve, through the bypass line as a second pulsed flow. A valve driving circuit periodically opens and closes the first valve and second valve at predetermined time schedules so that the second pulsed flow is superimposed upon the first pulsed flow to form a waveform in the conduit. Any desired pulsatile waveform can be obtained by adjusting the pulse width, the crest values, the delay time, etc., of the two pulsed flows.

摘要翻译： 在通过泵进行灌注时对流过导管的溶液施加周期性脉动的装置中，在泵下游的导管中设置第一阀，在第一阀的下游设有旁路管， 第二阀设置在旁通管线中，用于通过作为第二脉冲流通过旁通管线打开和关闭第一阀，以抽出形成在管道中的一些第一脉冲流。 阀驱动电路以预定的时间周期周期性地打开和关闭第一阀和第二阀，使得第二脉冲流叠加在第一脉冲流上以在导管中形成波形。 可以通过调节两个脉冲流的脉冲宽度，峰值，延迟时间等来获得所需的脉动波形。