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1.NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS 有权
标题翻译: 新型吡咯烷衍生的BETA 3 ADRENERGIC RECEPTOR AGONISTS公开(公告)号:US20160235727A1
公开(公告)日:2016-08-18
申请号:US15026267
申请日:2014-09-29
申请人: Kenneth Jay Barr , Mark E. Scott , Christopher F. Thompson , Neville Anthony , Carolyn Michele Cammarano , Raman Kumar Bakshi , Subhendu Kumar Mohanty , Chandra Sekhar Korapala , Prashant R. Latthe , Vyjayanthi N. Kambam , Sujit Kumar Sarkar , Jayanth Thiruvellore Thatai
发明人: Kenneth Jay Barr , Mark E. Scott , Christopher F. Thompson , Neville Anthony , Carolyn Michele Cammarano , Raman Kumar Bakshi , Subhendu Kumar Mohanty , Chandra Sekhar Korapala , Prashant R. Latthe , Vyjayanthi N. Kambam , Sujit Kumar Sarkar , Jayanth Thiruvellore Thatai
IPC分类号: A61K31/4439 , C07C53/18 , C07D401/14 , C07D413/14 , A61K31/444 , A61K31/517 , A61K31/497 , A61K31/501 , C07D471/04 , C07D495/04 , A61K31/519 , C07D401/06 , C07C53/06
CPC分类号: A61K31/4439 , A61K31/437 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K45/06 , C07B2200/07 , C07C53/06 , C07C53/18 , C07D207/08 , C07D207/09 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D413/14 , C07D471/04 , C07D495/04 , A61K2300/00
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of us ing the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。
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公开(公告)号:US09486448B2
公开(公告)日:2016-11-08
申请号:US15026267
申请日:2014-09-29
申请人: Kenneth Jay Barr , Mark E. Scott , Christopher F. Thompson , Neville Anthony , Carolyn Michele Cammarano , Raman Kumar Bakshi , Subhendu Kumar Mohanty , Chandra Sekhar Korapala , Prashant R. Latthe , Vyjayanthi N. Kambam , Sujit Kumar Sarkar , Jayanth Thiruvellore Thatai
发明人: Kenneth Jay Barr , Mark E. Scott , Christopher F. Thompson , Neville Anthony , Carolyn Michele Cammarano , Raman Kumar Bakshi , Subhendu Kumar Mohanty , Chandra Sekhar Korapala , Prashant R. Latthe , Vyjayanthi N. Kambam , Sujit Kumar Sarkar , Jayanth Thiruvellore Thatai
IPC分类号: C07C53/06 , C07C53/18 , C07D401/06 , C07D401/14 , C07D413/14 , C07D471/04 , A61K31/444 , A61K31/4439 , A61K31/497 , A61K31/501 , C07D495/04 , A61K31/519 , A61K31/517
CPC分类号: A61K31/4439 , A61K31/437 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K45/06 , C07B2200/07 , C07C53/06 , C07C53/18 , C07D207/08 , C07D207/09 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D413/14 , C07D471/04 , C07D495/04 , A61K2300/00
摘要: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译: 本发明提供式(I)化合物,其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。
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公开(公告)号:US20140038942A1
公开(公告)日:2014-02-06
申请号:US13983818
申请日:2012-02-10
申请人: Willem Frederik Johan Karstens , Mario Van Der Stelt , Jos Cals , Rita Corte Real Goncalves Azevedo , Kenneth Jay Barr , Hongjun Zhang , Richard Thomas Beresis , Dongshan Zhang , Xiaobang Duan
发明人: Willem Frederik Johan Karstens , Mario Van Der Stelt , Jos Cals , Rita Corte Real Goncalves Azevedo , Kenneth Jay Barr , Hongjun Zhang , Richard Thomas Beresis , Dongshan Zhang , Xiaobang Duan
IPC分类号: A61K31/4439 , A61K31/416 , C07D471/04 , A61K31/437 , A61K45/06 , C07D401/12 , A61K31/4709 , C07D413/12 , A61K31/4245 , C07D231/56 , C07D401/06
CPC分类号: A61K31/416 , A61K31/422 , A61K31/4245 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K45/06 , C07D231/56 , C07D401/06 , C07D401/12 , C07D403/10 , C07D409/14 , C07D413/12 , C07D413/14 , C07D471/04 , Y02A50/409
摘要: The present invention relates to compounds according to Formula (I) or a pharmaceutically acceptable salt or solvate thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or condition.
摘要翻译: 本发明涉及式(I)化合物或其药学上可接受的盐或溶剂合物。 这些化合物可用于治疗RORGAMMT介导的疾病或病症。
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公开(公告)号:US09095583B2
公开(公告)日:2015-08-04
申请号:US13983818
申请日:2012-02-10
申请人: Willem Frederik Johan Karstens , Mario Van Der Stelt , Jos Cals , Rita Corte Real Goncalves Azevedo , Kenneth Jay Barr , Hongjun Zhang , Richard Thomas Beresis , Dongshan Zhang , Xiaobang Duan
发明人: Willem Frederik Johan Karstens , Mario Van Der Stelt , Jos Cals , Rita Corte Real Goncalves Azevedo , Kenneth Jay Barr , Hongjun Zhang , Richard Thomas Beresis , Dongshan Zhang , Xiaobang Duan
IPC分类号: C07D401/10 , A61K31/4353 , A61K31/4439 , C07D231/56 , C07D401/06 , C07D401/12 , C07D403/10 , C07D409/14 , C07D413/12 , C07D413/14 , C07D471/04 , A61K31/416 , A61K31/4245 , A61K31/437 , A61K31/4709 , A61K45/06
CPC分类号: A61K31/416 , A61K31/422 , A61K31/4245 , A61K31/437 , A61K31/4439 , A61K31/4709 , A61K45/06 , C07D231/56 , C07D401/06 , C07D401/12 , C07D403/10 , C07D409/14 , C07D413/12 , C07D413/14 , C07D471/04 , Y02A50/409
摘要: The present invention relates to compounds according to Formula (I) or a pharmaceutically acceptable salt or solvate thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or condition.
摘要翻译: 本发明涉及式(I)化合物或其药学上可接受的盐或溶剂合物。 这些化合物可用于治疗RORGAMMT介导的疾病或病症。
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