专利检索 ap:("Kevin P. Anderson" OR "Ronnie C. Hanecak" OR "Chikateru Nozaki" OR "F. Andrew Dorr" OR "T. Jesse Kwoh") AND inv:"T. Jesse Kwoh" 第 1 页

1.

发明授权
Compositions and methods for treatment of hepatitis C virus-associated diseases 失效

公开(公告)号：US06995146B2

公开(公告)日：2006-02-07

申请号：US09853409

申请日：2001-05-11

申请人： Kevin P. Anderson , Ronnie C. Hanecak , Chikateru Nozaki , F. Andrew Dorr , T. Jesse Kwoh

发明人： Kevin P. Anderson , Ronnie C. Hanecak , Chikateru Nozaki , F. Andrew Dorr , T. Jesse Kwoh

IPC分类号： A61K31/711 , A61K31/7105 , C07H21/04 , C07H21/02

CPC分类号： C12N15/1131 , A61K38/00 , C07H21/00 , C07K14/005 , C12N2310/315 , C12N2310/318 , C12N2310/3181 , C12N2310/321 , C12N2310/322 , C12N2310/3233 , C12N2310/33 , C12N2310/334 , C12N2310/341 , C12N2310/346 , C12N2310/3521 , C12N2310/3527 , C12N2770/24222 , C12Q1/707 , C12N2310/3525

摘要： Antisense oligonucleotides are provided which are complementary to and hybridizable with at least a portion of HCV RNA and which are capable of inhibiting the function of the HCV RNA. These oligonucleotides can be administered to inhibit the activity of Hepatitis C virus in vivo or in vitro. These compounds can be used either prophylactically or therapeutically to reduce the severity of diseases associated with Hepatitis C virus, and for diagnosis and detection of HCV and HCV-associated diseases. Methods of using these compounds are also disclosed.