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    Guidewire with variable flexibility due to polymeric coatings
    1.
    发明授权
    Guidewire with variable flexibility due to polymeric coatings 失效
    导丝由于聚合物涂层而具有可变的柔性

    公开(公告)号：US5772609A

    公开(公告)日：1998-06-30

    申请号：US672637

    申请日：1996-06-28

    申请人： Kim Nguyen ,  Chi J. Chung ,  Thomas J. Palermo

    发明人： Kim Nguyen ,  Chi J. Chung ,  Thomas J. Palermo

    IPC分类号： A61M25/00 ,  A61B5/00

    CPC分类号： A61M25/09 ,  A61M2025/0046 ,  A61M2025/09091 ,  A61M2025/09133 ,  A61M2025/09175

    摘要： This invention is a guidewire for guiding a catheter and is used for accessing a targeted site within a lumen system in a body. The guidewire or guidewire section has a wire core, a distal tip region, a polymeric tie layer, and a lubricious coating. The tie layer is preferably constructed to provide for sections of varying flexibility along the length of the guidewire. Variations of the tie layer provide for axially spaced sections of varying flexibility, radially layers of varying flexibility of both. In a special variation, the tie layer is constructed with at least one section providing increased stiffness distally.

    摘要翻译： 本发明是用于引导导管的导丝，并且用于进入体内管腔系统内的目标部位。 导线或导丝部分具有线芯，远端尖端区域，聚合物连接层和光滑涂层。 连接层优选构造成沿着导丝的长度提供具有不同柔性的部分。 连接层的变化提供了具有不同柔性的轴向间隔的部分，两者具有不同柔性的径向层。 在一个特殊的变化中，连接层被构造成具有至少一个向远端提供增加的刚度的部分。

    Locator and closure device and method of use
    2.
    发明授权
    Locator and closure device and method of use 有权
    定位器和闭合装置及其使用方法

    公开(公告)号：US08088144B2

    公开(公告)日：2012-01-03

    申请号：US11244944

    申请日：2005-10-05

    申请人： Richard S. Ginn ,  Thomas J. Palermo

    发明人： Richard S. Ginn ,  Thomas J. Palermo

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2017/2923 ,  A61B2090/0807

    摘要： A device which is capable of both locating a punctured blood vessel wall and sealing the puncture in the vessel and a method of using the device. In one embodiment, the device includes an elongate deployment member having a releasable sealing element disposed within a distal end and an elongated indicator member having a proximal end and a distal end. The deployment member is coupled to a first actuator configured to retract the deployment member relative to the sealing element. The indicator member extends through a lumen in the deployment member such that the distal end of said the indicator member extends distally of the distal end of the deployment member. The indicator member is also coupled to a second actuator configured to retract the indicator member relative to the deployment member.

    摘要翻译： 能够将穿刺的血管壁定位并将穿刺密封在容器中的装置以及使用该装置的方法。 在一个实施例中，该装置包括具有设置在远端内的可释放密封元件的细长展开构件和具有近端和远端的细长指示器构件。 展开构件联接到构造成相对于密封元件缩回展开构件的第一致动器。 指示器构件延伸穿过展开构件中的内腔，使得所述指示构件的远端延伸到展开构件的远端的远侧。 指示器构件还联接到被配置为使指示器构件相对于展开构件缩回的第二致动器。

    Locator and closure device and method of use
    5.
    发明授权
    Locator and closure device and method of use 有权
    定位器和闭合装置及其使用方法

    公开(公告)号：US09044211B2

    公开(公告)日：2015-06-02

    申请号：US13331292

    申请日：2011-12-20

    申请人： Richard S. Ginn ,  Thomas J. Palermo

    发明人： Richard S. Ginn ,  Thomas J. Palermo

    IPC分类号： A61B17/08 ,  A61B17/00 ,  A61B17/29 ,  A61B19/00

    CPC分类号： A61B17/0057 ,  A61B2017/00654 ,  A61B2017/00672 ,  A61B2017/2923 ,  A61B2090/0807

    摘要： The present invention is directed to a device which is capable of both locating a punctured blood vessel wall and sealing the puncture in the vessel and to the method of using the device as well. In one embodiment, the device includes an elongate deployment member having a sealing element releasably disposed within a distal end thereof, said deployment member being coupled to a first actuator configured to retract said deployment member relative to said sealing element, and an elongated indicator member having a proximal end and a distal end, said indicator member extending through a lumen in said deployment member such that the distal end of said indicator member extends distally of the distal end of the deployment member, and said indicator member being coupled to a second actuator configured to retract said indicator member relative to said deployment member.

    摘要翻译： 本发明涉及一种能够将穿刺的血管壁定位并密封容器中的穿刺以及使用该装置的方法的装置。 在一个实施例中，该装置包括细长展开构件，其具有可释放地设置在其远端内的密封元件，所述展开构件联接到构造成相对于所述密封元件缩回所述展开构件的第一致动器，以及细长的指示器构件， 近端和远端，所述指示器构件延伸穿过所述展开构件中的内腔，使得所述指示器构件的远端延伸到展开构件的远端的远侧，并且所述指示器构件联接到第二致动器构造 以相对于所述展开构件缩回所述指示器构件。

    Inflatable manipulator for organ positioning during surgery
    6.
    发明授权
    Inflatable manipulator for organ positioning during surgery 有权
    充气器官手术器官定位

    公开(公告)号：US06371910B1

    公开(公告)日：2002-04-16

    申请号：US09438811

    申请日：1999-11-10

    申请人： Hans J. Zwart ,  Lawrence R. Tyler ,  Thomas J. Palermo ,  Kevin Van Bladel ,  Roderick A. Young ,  James E. Jervis

    发明人： Hans J. Zwart ,  Lawrence R. Tyler ,  Thomas J. Palermo ,  Kevin Van Bladel ,  Roderick A. Young ,  James E. Jervis

    IPC分类号： A61B132

    CPC分类号： A61B17/0218 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61B2017/00084 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/320048 ,  A61B2090/032 ,  A61B2090/034 ,  A61B2090/061 ,  A61B2090/064

    摘要： An inflatable manipulator for organ manipulation during surgery is disclosed. The system typically includes an inflatable balloon connected to an infusion source where the balloon is either coupled to a relatively rigid platform or fitted with a positioning structure such as a pocket. In open heart surgery, the platform is used to position and stabilize the balloon under the heart. In minimally invasive surgery, the balloon fitted with the pocket and can be rolled into a narrow configuration and inserted through a small incision using an insertion device. The insertion device can then be removed once the manipulator is in position. In use, the balloon of the manipulator is inflated by the infusion source thereby elevating and tilting the organ to the desired position for surgical access. Systems including multiple chamber manipulators each with a separate infusion source are also disclosed, as are combined methods for cooling organs during surgery and for using the manipulators to separate adhesions.

    摘要翻译： 公开了一种用于手术中器官操作的充气操纵器。 该系统通常包括连接到输注源的可充气气囊，其中气囊被联接到相对刚性的平台或者配合有定位结构例如口袋。 在心脏直视手术中，平台用于在心脏下定位和稳定气囊。 在微创手术中，气囊装配有口袋，并且可以卷成狭窄的构造并且通过使用插入装置的小切口插入。 一旦操纵器就位就可以将插入装置移除。 在使用中，操纵器的球囊被输注源膨胀，从而升高并将器官倾斜到期望的位置以进行外科手术。 还公开了包括具有单独输注源的多个腔室操纵器的系统，以及用于在手术期间冷却器官和使用操纵器分离粘连的组合方法。

    Inflatable manipulator for organ positioning during surgery and method of use
    7.
    发明授权
    Inflatable manipulator for organ positioning during surgery and method of use 失效
    用于手术器官定位的充气手术器械和使用方法

    公开(公告)号：US6015382A

    公开(公告)日：2000-01-18

    申请号：US951799

    申请日：1997-10-16

    申请人： Hans J. Zwart ,  Lawrence R. Tyler ,  Thomas J. Palermo ,  Kevin Van Bladel ,  Roderick A. Young ,  James E. Jervis

    发明人： Hans J. Zwart ,  Lawrence R. Tyler ,  Thomas J. Palermo ,  Kevin Van Bladel ,  Roderick A. Young ,  James E. Jervis

    IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/32 ,  A61B19/00

    CPC分类号： A61B17/0218 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61B2017/00084 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/320048 ,  A61B2090/032 ,  A61B2090/034 ,  A61B2090/061 ,  A61B2090/064

    摘要： An inflatable manipulator for organ manipulation during surgery is disclosed. The system typically includes an inflatable balloon connected to an infusion source where the balloon is either coupled to a relatively rigid platform or fitted with a positioning structure such as a pocket. In open heart surgery, the platform is used to position and stabilize the balloon under the heart. In minimally invasive surgery, the balloon fitted with the pocket and can be rolled into a narrow configuration and inserted through a small incision using an insertion device. The insertion device can then be removed once the manipulator is in position. In use, the balloon of the manipulator is inflated by the infusion source thereby elevating and tilting the organ to the desired position for surgical access. Systems including multiple chamber manipulators each with a separate infusion source are also disclosed, as are combined methods for cooling organs during surgery and for using the manipulators to separate adhesions.

    摘要翻译： 公开了一种用于手术中器官操作的充气操纵器。 该系统通常包括连接到输注源的可充气气囊，其中气囊被联接到相对刚性的平台或者配合有定位结构例如口袋。 在心脏直视手术中，平台用于在心脏下定位和稳定气囊。 在微创手术中，气囊装配有口袋，并且可以卷成狭窄的构造并且通过使用插入装置的小切口插入。 一旦操纵器就位就可以将插入装置移除。 在使用中，操纵器的球囊被输注源膨胀，从而升高并将器官倾斜到期望的位置以进行外科手术。 还公开了包括具有单独输注源的多个腔室操纵器的系统，以及用于在手术期间冷却器官和使用操纵器分离粘连的组合方法。