公开(公告)号：US20040096485A1

公开(公告)日：2004-05-20

申请号：US10299161

申请日：2002-11-19

申请人： Kimberly-Clark Worldwide, Inc.

发明人： David W. Koenig ,  Jamie Joseph Van Gompel

IPC分类号： A61K035/72 ,  A61K035/80 ,  A61K009/70 ,  A61K035/78

CPC分类号： A61K8/0208 ,  A61K8/97 ,  A61K2800/70 ,  A61K2800/78 ,  A61Q19/00 ,  A61Q19/08

摘要： Disclosed are methods and products such as wet wipes and absorbents capable of providing a skin health benefit when utilized in the intended fashion. More specifically, the products described herein comprise an agent, such as a botanical extract, which is capable of increasing the activity of sphingomyelinase according to a Sphingomyelinase Activity Screening Test and/or decreasing the activity of ceramidase according to a Ceramidase Activity Screening Test. By increasing the activity of sphingomyelinase and/or decreasing the activity of ceramidase, the agents in combination with the products described herein are able to maintain or increase the level of ceramides in the skin leading to improved skin health.

摘要翻译： 公开了当以预期的方式使用时能够提供皮肤健康益处的湿巾和吸收剂的方法和产品。 更具体地，本文所述的产品包含根据鞘磷脂酶活性筛选试验能够增加鞘磷脂酶的活性和/或根据神经酰胺酶活性筛选试验降低神经酰胺酶的活性的试剂，例如植物提取物。 通过增加鞘磷脂酶的活性和/或降低神经酰胺酶的活性，与本文所述产品组合的药剂能够维持或增加皮肤中神经酰胺的水平，从而改善皮肤健康。