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公开(公告)号：US20220305459A1
公开(公告)日：2022-09-29
申请号：US17834608
申请日：2022-06-07
发明人： Nisar ULLAH , Abdul Waheed , Muhammad Mansha , Izzat Wajih Kazi
摘要： A crosslinked resin made up of polymerized units of a linear polyamine with at least 3 primary and/or secondary amine functionalities and a bisacrylamide. The crosslinked polymers are porous spherical particles with a BET surface area in the range of 50-120 m2/g. A method of the synthesizing the crosslinked polymer is specified. A method for using the crosslinked resin as an adsorbent material in removing pollutants including organic dyes (e.g. Congo red, Rhodamine B) and heavy metals from an aqueous solution or an industrial wastewater sample is also described.
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公开(公告)号：US10023527B2
公开(公告)日：2018-07-17
申请号：US15487116
申请日：2017-04-13
发明人： Muhammad Mansha , Yasir Abbas , Nisar Ullah
IPC分类号： C07C231/12
摘要： A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.
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3.发明授权公开(公告)号：US09688611B2
公开(公告)日：2017-06-27
申请号：US14918658
申请日：2015-10-21
发明人： Muhammad Mansha , Yasir Abbas , Nisar Ullah
IPC分类号： C07C227/16 , A61K31/198 , A61K38/19
CPC分类号： C07C231/12 , A61K31/198 , A61K38/191 , C07C227/16 , C07C233/51 , C07C229/36
摘要： A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.
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公开(公告)号：US11435288B1
公开(公告)日：2022-09-06
申请号：US17745358
申请日：2022-05-16
发明人： Shahid Ali , Muhammad Mansha , Safyan Akram Khan , Nadeem Baig
IPC分类号： G01N21/64 , G01N33/2028 , G01N21/17
摘要： A method for detecting mercury (Hg2+) ions in an aqueous solution is described. The method includes contacting the aqueous solution with a chemosensor to form a mixture; and monitoring a change in a fluorescence emission profile of the chemosensor in the mixture to determine the presence or absence of Hg2+ ions in the aqueous solution. The chemosensor includes pyrene silica nanoparticles where at least one pyrene is bonded to a surface of a silica nanoparticle through an amide bond with a formula of, pyrene-C(═O)NHR-silica nanoparticle, and where R is an alkyl chain.
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公开(公告)号：US10329245B2
公开(公告)日：2019-06-25
申请号：US15928906
申请日：2018-03-22
发明人： Muhammad Mansha , Yasir Abbas , Nisar Ullah
IPC分类号： A61K38/19 , A61K31/198 , C07C227/16 , C07C229/36 , C07C231/12 , C07C233/51
摘要： A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.
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公开(公告)号：US11351520B2
公开(公告)日：2022-06-07
申请号：US16679730
申请日：2019-11-11
发明人： Nisar Ullah , Abdul Waheed , Muhammad Mansha , Izzat Wajih Kazi
IPC分类号： B01J20/26 , C08G61/12 , B01J20/28 , C02F1/28 , C02F1/00 , C02F101/20 , C02F101/30 , C02F101/22
摘要： A crosslinked resin made up of polymerized units of a linear polyamine with at least 3 primary and/or secondary amine functionalities and a bisacrylamide. The crosslinked polymers are porous spherical particles with a BET surface area in the range of 50-120 m2/g. A method of the synthesizing the crosslinked polymer is specified. A method for using the crosslinked resin as an adsorbent material in removing pollutants including organic dyes (e.g. Congo red, Rhodamine B) and heavy metals from an aqueous solution or an industrial wastewater sample is also described.
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公开(公告)号：US20180208546A1
公开(公告)日：2018-07-26
申请号：US15928906
申请日：2018-03-22
发明人： Muhammad Mansha , Yasir Abbas , Nisar Ullah
IPC分类号： C07C231/12
CPC分类号： C07C231/12 , A61K31/198 , A61K38/191 , C07C227/16 , C07C233/51 , C07C229/36
摘要： A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is disclosed. The method proceeds through an O-allylated tyrosine-based compound, such as compound 3 and preferably comprises [3,3] sigmatropic Claisen rearrangement and olefin cross metathesis reactions. In addition, a pharmaceutical composition comprising a compound of formula (I) a tumor necrosis factor (TNF) related apoptosis inducing ligand (TRAIL) and a pharmaceutically acceptable carrier or excipient is disclosed.
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公开(公告)号：US11618006B2
公开(公告)日：2023-04-04
申请号：US17834608
申请日：2022-06-07
发明人： Nisar Ullah , Abdul Waheed , Muhammad Mansha , Izzat Wajih Kazi
IPC分类号： B01J20/26 , C08G61/12 , B01J20/28 , C02F1/28 , C02F1/00 , C02F101/20 , C02F101/30 , C02F101/22
摘要： A crosslinked resin made up of polymerized units of a linear polyamine with at least 3 primary and/or secondary amine functionalities and a bisacrylamide. The crosslinked polymers are porous spherical particles with a BET surface area in the range of 50-120 m2/g. A method of the synthesizing the crosslinked polymer is specified. A method for using the crosslinked resin as an adsorbent material in removing pollutants including organic dyes (e.g. Congo red, Rhodamine B) and heavy metals from an aqueous solution or an industrial wastewater sample is also described.
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公开(公告)号：US10882948B2
公开(公告)日：2021-01-05
申请号：US15955768
申请日：2018-04-18
摘要： A copolymer containing carbazole- and cyanovinylene-based moieties, a photoelectrode comprising a metal oxide substrate and the copolymer as a photoelectrocatalyst component to the photoelectrode, as well as a photoelectrochemical cell including the photoelectrode. Methods of producing the copolymers, and methods of using the photoelectrochemical cell to produce hydrogen gas and oxygen gas through water splitting are also provided.
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