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公开(公告)号:US5036010A
公开(公告)日:1991-07-30
申请号:US515006
申请日:1990-04-26
申请人: King S. Lam , Jacqueline Mattei , John E. Leet , James A. Matson , Koji Tomita , Murray A. Kaplan
发明人: King S. Lam , Jacqueline Mattei , John E. Leet , James A. Matson , Koji Tomita , Murray A. Kaplan
IPC分类号: C12P1/06
CPC分类号: C12P1/06 , Y10S435/898
摘要: A new antitumor antibiotic designated BMY-40800 is produced by fermentation of Streptomyces hygroscopicus ATCC 53653. The new compound inhibits the growth of tumors in experimental animals.
摘要翻译: 名称为BMY-40800的新型抗肿瘤抗生素通过发酵吸水链霉菌ATCC 53653产生。新化合物抑制实验动物的肿瘤生长。
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公开(公告)号:US4994271A
公开(公告)日:1991-02-19
申请号:US155778
申请日:1988-02-16
申请人: Kin S. Lam , Jacqueline Mattei , John E. Leet , James A. Matson , Koji Tomita , Murray A. Kaplan
发明人: Kin S. Lam , Jacqueline Mattei , John E. Leet , James A. Matson , Koji Tomita , Murray A. Kaplan
CPC分类号: C12P1/06
摘要: A new antitumor antibiotic designated BMY-40800 is produced by fermentation of Streptomyces hygroscopicus ATCC 53653. The new compound inhibits the growth of tumors in experimental animals.
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公开(公告)号:US5326754A
公开(公告)日:1994-07-05
申请号:US63383
申请日:1993-05-18
IPC分类号: C07H19/044 , C07D273/00 , A61K31/00
CPC分类号: A61K31/70 , C07H19/044
摘要: An antitumor antibiotic designated BMY-41219 is produced by fermentation of Saccharothrix aerocolonigenes ATCC 39243. The BMY-41219 antibiotic exhibits antitumor activity.
摘要翻译: 称为BMY-41219的抗肿瘤抗生素是通过发酵糖酵母ATCC 39243产生的.BMY-41219抗生素具有抗肿瘤活性。
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公开(公告)号:US5468849A
公开(公告)日:1995-11-21
申请号:US216075
申请日:1994-03-21
IPC分类号: C07H17/00 , A61K31/70 , A61K31/7042 , A61K31/7052 , A61P35/00 , C07H19/044 , C07H19/23 , C12P19/28 , C12P19/44 , C12R1/01 , C12R1/645 , C07G3/00 , C07H11/00 , C07H17/02
CPC分类号: C07H19/044 , C12P19/28
摘要: Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin analogs having advantageous antitumor properties.
摘要翻译: 在产生克雷霉素生产菌株的发酵过程中向培养基中加入某些色氨酸类似物导致产生具有有利抗肿瘤性质的新的雷贝卡霉素类似物。
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公开(公告)号:US5344823A
公开(公告)日:1994-09-06
申请号:US830969
申请日:1992-02-06
IPC分类号: C07H19/044 , A61K31/00
CPC分类号: A61K31/70 , C07H19/044
摘要: A new antitumor antibiotic designated BMY-41219 is produced by fermentation of Saccharothrix aerocolonigenes ATCC 39243. The BMY-41219 antibiotic exhibits antitumor activity.
摘要翻译: 名称为BMY-41219的新型抗肿瘤抗生素是通过发酵产糖杆菌ATCC 39243产生的.BMY-41219抗生素具有抗肿瘤活性。
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公开(公告)号:US5158938A
公开(公告)日:1992-10-27
申请号:US764116
申请日:1991-09-23
IPC分类号: C07H19/044 , C12P19/28
CPC分类号: C12P19/28 , C07H19/044
摘要: Addition of bromine to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of a new rebeccamycin derivative having advantageous antineoplastic properties.
摘要翻译: 在克雷霉素生产菌株的发酵过程中向培养基中加入溴导致产生具有有利抗肿瘤性质的新的雷贝卡霉素衍生物。
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公开(公告)号:US5073633A
公开(公告)日:1991-12-17
申请号:US608773
申请日:1990-11-05
IPC分类号: C07H19/04
CPC分类号: C07H19/04
摘要: An antitumor antibiotic designated BMY-41950 is produced by fermentation of Streptomyces staurosporeus ATCC 55006 or Streptomyces hygroscopicus ATCC 53730. The BMY-41950 antibiotic exhibits both antimicrobial and antitumor activities.
摘要翻译: 名称为BMY-41950的抗肿瘤抗生素通过Stautomyces staurosporeus ATCC 55006或吸水链霉菌ATCC 53730的发酵产生。BMY-41950抗生素具有抗微生物和抗肿瘤活性。
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公开(公告)号:US5015578A
公开(公告)日:1991-05-14
申请号:US482364
申请日:1990-02-20
IPC分类号: C12P17/18 , A61K31/55 , A61K31/70 , A61P31/04 , A61P35/00 , C07D498/22 , C07H19/04 , C07H19/044 , C12N1/20 , C12R1/465 , C12R1/55
CPC分类号: C07H19/04 , Y10S435/898
摘要: A new antitumor antibiotic designated BMY-41950 is produced by fermentation of Streptomyces staurosporeus ATCC 55006 or Streptomyces hygroscopicus ATCC 53730. The BMY-41950 antibiotic exhibits both antimicrobial and antitumor activities.
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