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公开(公告)号：US6001858A
公开(公告)日：1999-12-14
申请号：US849259
申请日：1997-06-02
申请人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemuller , Terence Hopkins
发明人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemuller , Terence Hopkins
CPC分类号： A01N51/00 , A01N61/00 , Y10S514/83
摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following compositionagonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation;solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation;if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation;if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.
摘要翻译： PCT No.PCT / EP95 / 04667 Sec。 371日期：1997年6月2日 102（e）日期1997年6月2日PCT提交1995年11月27日PCT公布。 第WO96 / 17520号公报 日期1996年6月13日本发明涉及用于对动物进行寄生昆虫的真皮对照的制剂，其具有以下组成的组合物：浓度为1至20重量％的昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，基于总体 制剂重量; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。
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公开(公告)号：US20060281792A1
公开(公告)日：2006-12-14
申请号：US11508055
申请日：2006-08-21
申请人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemuller , Terence Hopkins
发明人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemuller , Terence Hopkins
IPC分类号： A01N43/40
CPC分类号： A01N51/00 , A01N61/00 , Y10S514/83 , A01N25/02 , A01N2300/00
摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.
摘要翻译： 本发明涉及用于对动物进行寄生昆虫的真皮控制的制剂，其具有下列成分：昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，其浓度为制剂总重量的1至20重量％; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。
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公开(公告)号：US06372765B1
公开(公告)日：2002-04-16
申请号：US09435271
申请日：1999-11-05
申请人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemüller , Terence Hopkins
发明人： Kirkor Sirinyan , Hubert Dorn , Richard Kujanek , Klemens Krieger , Ulrich Heukamp , Doris Hackemüller , Terence Hopkins
IPC分类号： H01N5100
CPC分类号： A01N51/00 , A01N61/00 , Y10S514/83 , A01N25/02 , A01N2300/00
摘要： The present invention relates to formulations for the dermal control of parasitic insects of animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.
摘要翻译： 本发明涉及用于真皮对照动物寄生昆虫的制剂，其具有以下配合物或者拮抗剂，其浓度为制剂总重量的1至20重量％的昆虫的烟碱能乙酰胆碱受体;溶剂 基于组合物的总重量，基于苄基醇或任选取代的吡咯烷酮，其浓度为至少20重量％;如果需要，还可以使用浓度为5.0至最高的环状碳酸酯或内酯的另外的溶剂 基于制剂的总重量为80重量％;如果需要，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的更多助剂 基于制剂的总重量。
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公开(公告)号：US07384938B2
公开(公告)日：2008-06-10
申请号：US10347003
申请日：2003-01-17
申请人： Kirkor Sirinyan , Hubert Dorn , Ulrich Heukamp
发明人： Kirkor Sirinyan , Hubert Dorn , Ulrich Heukamp
IPC分类号： A01N43/40 , A61K31/54 , A61K31/535
摘要： The present invention relates to water-containing formulations for the dermal control of parasitic insects on animals, having the following composition a) agonists or antagonists of the nicotinic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; b) water in a concentration of from 2.5 to 15% by weight; c) solvents from the group alcohols such as benzyl alcohol, tetrahydrofuryl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; d) solvents from the group of the cyclic carbonates or lactones in a concentration of from 5 to up to 50% by weight based on the overall weight of the formulation; e) if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.
摘要翻译： 本发明涉及用于对动物进行寄生昆虫的真皮控制的含水制剂，具有以下组成：a）基于总体的浓度为1至20重量％的昆虫烟碱乙酰胆碱受体的激动剂或拮抗剂 制剂重量; b）浓度为2.5至15重量％的水; c）基于配制物的总重量的至少20重量％的浓度的醇类如苄醇，四氢呋喃醇或任选取代的吡咯烷酮的溶剂; d）来自环状碳酸酯或内酯基团的溶剂，其浓度为制剂总重量的5至50重量％; e）如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。
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公开(公告)号：US06300348B1
公开(公告)日：2001-10-09
申请号：US09142892
申请日：1998-09-16
申请人： Kirkor Sirinyan , Ulrich Heukamp , Hubert Dorn , Ronald Helmut Stöcker , Rainer Sonneck , Rosemary Peter
发明人： Kirkor Sirinyan , Ulrich Heukamp , Hubert Dorn , Ronald Helmut Stöcker , Rainer Sonneck , Rosemary Peter
IPC分类号： H01N5100
CPC分类号： A01N51/00 , Y10S514/83 , A01N43/28 , A01N25/02 , A01N2300/00
摘要： The present invention relates to formulations for the dermal control of parasitic insects on humans, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 0.0001 to 12.5% by weight based on the overall weight of the formulation; solvents from the group of the cyclic carbonates in a concentration of from 2.5 to 99.9999% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of the alcohols in a concentration of from 0 to 95% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group of the thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0 up to 30% by weight based on the overall weight of the formulation.
摘要翻译： 本发明涉及用于对人类寄生虫进行真皮控制的制剂，其具有以下配合物，其浓度为制剂总重量的0.0001至12.5重量％的昆虫的烟碱能乙酰胆碱受体的组成或拮抗剂;溶剂 来自环状碳酸酯的基团，其浓度为制剂总重量的2.5至99.9999重量％;如果需要，还可使用浓度为0至95重量％的醇的其它溶剂 基于制剂的总重量;如果需要，来自增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的组的其它助剂的浓度为0至30重量％，基于 制剂的总重量。
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