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    Parasiticide formulations suitable for dermal application
    1.
    发明授权
    Parasiticide formulations suitable for dermal application 失效
    适用于皮肤应用的寄生虫制剂

    公开(公告)号：US6001858A

    公开(公告)日：1999-12-14

    申请号：US849259

    申请日：1997-06-02

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    IPC分类号： A01N43/36 ,  A01N43/40 ,  A01N43/50 ,  A01N43/78 ,  A01N43/86 ,  A01N51/00 ,  A01N61/00

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83

    摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following compositionagonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation;solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation;if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation;if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： PCT No.PCT / EP95 / 04667 Sec。 371日期：1997年6月2日 102（e）日期1997年6月2日PCT提交1995年11月27日PCT公布。 第WO96 / 17520号公报 日期1996年6月13日本发明涉及用于对动物进行寄生昆虫的真皮对照的制剂，其具有以下组成的组合物：浓度为1至20重量％的昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，基于总体 制剂重量; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。

    Parasiticide formulations suitable for dermal application
    2.
    发明申请
    Parasiticide formulations suitable for dermal application 审中-公开
    适用于皮肤应用的寄生虫制剂

    公开(公告)号：US20060281792A1

    公开(公告)日：2006-12-14

    申请号：US11508055

    申请日：2006-08-21

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemuller ,  Terence Hopkins

    IPC分类号： A01N43/40

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83 ,  A01N25/02 ,  A01N2300/00

    摘要： The present invention relates to formulations for the dermal control of parasitic insects on animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： 本发明涉及用于对动物进行寄生昆虫的真皮控制的制剂，其具有下列成分：昆虫的烟碱能乙酰胆碱受体的激动剂或拮抗剂，其浓度为制剂总重量的1至20重量％; 基于制剂的总重量，来自组苯甲醇或任选取代的吡咯烷酮的溶剂的浓度为至少20重量％; 如果需要，基于制剂的总重量，浓度为5.0至80重量％的来自环状碳酸酯或内酯的另外的溶剂; 如果需要，基于制剂的总重量，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的其它助剂。

    Parasiticidal formulations that can be applied dermally
    3.
    发明授权
    Parasiticidal formulations that can be applied dermally 有权
    可以皮肤施用的寄生性制剂

    公开(公告)号：US06372765B1

    公开(公告)日：2002-04-16

    申请号：US09435271

    申请日：1999-11-05

    申请人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemüller ,  Terence Hopkins

    发明人： Kirkor Sirinyan ,  Hubert Dorn ,  Richard Kujanek ,  Klemens Krieger ,  Ulrich Heukamp ,  Doris Hackemüller ,  Terence Hopkins

    IPC分类号： H01N5100

    CPC分类号： A01N51/00 ,  A01N61/00 ,  Y10S514/83 ,  A01N25/02 ,  A01N2300/00

    摘要： The present invention relates to formulations for the dermal control of parasitic insects of animals, having the following composition agonists or antagonists of the nicotinergic acetylcholine receptors of insects in a concentration of from 1 to 20% by weight based on the overall weight of the formulation; solvents from the group benzyl alcohol or optionally substituted pyrrolidones in a concentration of at least 20% by weight based on the overall weight of the formulation; if desired, further solvents from the group consisting of cyclic carbonates or lactones in a concentration of from 5.0 up to 80% by weight based on the overall weight of the formulation; if desired, further auxiliaries from the group thickeners, spreading agents, colorants, antioxidants, propellants, preservatives, adhesives, emulsifiers, in a concentration of from 0.025 up to 10% by weight based on the overall weight of the formulation.

    摘要翻译： 本发明涉及用于真皮对照动物寄生昆虫的制剂，其具有以下配合物或者拮抗剂，其浓度为制剂总重量的1至20重量％的昆虫的烟碱能乙酰胆碱受体;溶剂 基于组合物的总重量，基于苄基醇或任选取代的吡咯烷酮，其浓度为至少20重量％;如果需要，还可以使用浓度为5.0至最高的环状碳酸酯或内酯的另外的溶剂 基于制剂的总重量为80重量％;如果需要，浓度为0.025至10重量％的来自组增稠剂，铺展剂，着色剂，抗氧化剂，推进剂，防腐剂，粘合剂，乳化剂的更多助剂 基于制剂的总重量。

    NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES
    5.
    发明申请
    NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES 审中-公开
    来自真菌菌株的新型24位CYCLOOCTADEPSIPEPTISES及其作为安非他明或内给药的用途

    公开(公告)号：US20120302496A1

    公开(公告)日：2012-11-29

    申请号：US13514538

    申请日：2010-12-07

    申请人： Achim Harder ,  Klemens Krieger ,  Thi Lam Huong Pham ,  Thanh Dam Huynh ,  Irmtraut Zaspel ,  Dietrich Ewald ,  Clemens Mügge ,  Hardy Weisshoff

    发明人： Achim Harder ,  Klemens Krieger ,  Thi Lam Huong Pham ,  Thanh Dam Huynh ,  Irmtraut Zaspel ,  Dietrich Ewald ,  Clemens Mügge ,  Hardy Weisshoff

    IPC分类号： C07K11/02 ,  A61P33/10 ,  A61P33/00 ,  C12P21/04 ,  A61K38/15

    CPC分类号： C07D273/00

    摘要： The present invention relates firstly to the discovery of the previously unknown 24-membered cyclooctadepsipeptides PF1022-V, PF1022-W, XRB-C894, XRB-C942, XRB-C976, XRB-C1010, XRB-C1044, XRB-E922, XRB-E956, XRB-E990, XRB-E1024, XRB-S958, XRB-S992, XRB-S1026, XRB-S1060 (in various isomeric forms) and to the processes for the preparation of the abovementioned cyclooctadepsipeptides by means of the fungal strains from the family Xylariaceae, in particular the genera Rosellinia and Coniolariella, and by means of the mitosporic fungal strains from the groups Fusarium, Beauveria and Verticillium (orders Hypocreales and Phyllachorales), and by means of the enzymatic preparations isolated from these fungal strains, and secondly to the use of these strains for the preparation of the abovementioned novel cyclooctadepsipeptides and to the use of bassianolide and of the abovementioned novel cyclooctadepsipeptides individually or as a mixture, as anthelmintics or endoparasiticides.

    摘要翻译： 本发明首先涉及以前未知的24-元环十二肽肽PF1022-V，PF1022-W，XRB-C894，XRB-C942，XRB-C976，XRB-C1010，XRB-C1044，XRB-E922，XRB- E956，XRB-E990，XRB-E1024，XRB-S958，XRB-S992，XRB-S1026，XRB-S1060（各种异构形式）以及上述环庚三烯肽的制备方法， 以及通过来自镰刀菌，白僵菌和轮枝孢属（命名为Hypocreales和Phyllachorales）的分枝杆菌真菌菌株，并通过从这些真菌菌株分离的酶制剂，以及其次为 使用这些菌株制备上述新型的环庚三烯肽，以及使用巴西酰胺和上述新型的环辛酸肽单独或作为混合物作为驱肠虫剂或内寄生虫杀菌剂。