公开(公告)号：US07288272B2

公开(公告)日：2007-10-30

申请号：US11246442

申请日：2005-10-06

申请人： Koji Ochiai ,  Nobuko Ueda

发明人： Koji Ochiai ,  Nobuko Ueda

IPC分类号： A61K36/87

CPC分类号： A61K8/97 ,  A61K36/87 ,  A61Q19/00

摘要： To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds.

摘要翻译： 提供一种制造多酚的方法，其可以从葡萄籽中工业制造含有水溶性原花青素的多酚。

公开(公告)号：US07838051B2

公开(公告)日：2010-11-23

申请号：US11852722

申请日：2007-09-10

申请人： Koji Ochiai ,  Nobuko Ueda

发明人： Koji Ochiai ,  Nobuko Ueda

IPC分类号： A61K36/87

CPC分类号： A61K8/97 ,  A61K36/87 ,  A61Q19/00

摘要： To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds. The seeds of grape berries dried after squeezing out the juice are separated into grape seeds and peel with a separation apparatus, and the grape seeds are stirred in a washing machine to remove contamination thoroughly. The grape seeds are charged into a boiling kettle and heated for the prescribed time at the prescribed temperature. Then, germination is induced in a curing kettle maintained at the prescribed temperature preferred for the germination. The grape seeds in which germination or germination and differentiation have advanced are crushed, mixed with water to obtain an emulsified state, and a salt is added, if desired. After a known desalting treatment has been conducted with respect to an aqueous solution portion, water is evaporated with a vacuum apparatus to obtain polyphenols comprising proanthocyanidins converted to a water soluble form.

摘要翻译： 提供一种制造多酚的方法，其可以从葡萄籽中工业制造含有水溶性原花青素的多酚。 榨出果汁后干燥的葡萄浆果的种子被分离成葡萄籽并用分离装置剥离，并将葡萄籽在洗衣机中搅拌以彻底清除污染物。 将葡萄籽装入沸水壶中并在规定温度下加热规定的时间。 然后，在维持在规定温度下用于发芽的固化釜中诱导发芽。 将发芽或发芽和分化进行的葡萄籽粉碎，与水混合以获得乳化状态，如果需要，加入盐。 在对水溶液部分进行已知的脱盐处理之后，用真空装置蒸发水，得到包含转化为水溶性形式的原花色素的多酚。

公开(公告)号：US20080008812A1

公开(公告)日：2008-01-10

申请号：US11849213

申请日：2007-08-31

申请人： Koji OCHIAI ,  Nobuko Ueda

发明人： Koji OCHIAI ,  Nobuko Ueda

IPC分类号： A23B9/24 ,  A01C1/02

CPC分类号： A23L7/20 ,  A23B9/20 ,  A23B9/30 ,  A23L7/152 ,  A23L25/20

摘要： A method and apparatus for increased yields of water-soluble polyphenols from plant seeds is provided. The method includes inducing seed germination within a selected range of temperatures. The method also includes inducing germination in an atmosphere having elevated carbon oxygen concentration and/or a reduced concentration of oxygen. The method further includes exposing the seeds to light and extracting water-soluble polyphenols with an aqueous solution without adding an organic solvent such as alcohol.

摘要翻译： 提供了一种从植物种子提高水溶性多酚产量的方法和装置。 该方法包括在选定的温度范围内诱导种子发芽。 该方法还包括在具有升高的碳氧浓度和/或降低的氧浓度的气氛中诱导发芽。 该方法还包括将种子暴露于光下，并用水溶液萃取水溶性多酚，而不加入有机溶剂如醇。

公开(公告)号：US08756861B2

公开(公告)日：2014-06-24

申请号：US11849213

申请日：2007-08-31

申请人： Koji Ochiai ,  Nobuko Ueda

发明人： Koji Ochiai ,  Nobuko Ueda

IPC分类号： A01C1/02

CPC分类号： A23L7/20 ,  A23B9/20 ,  A23B9/30 ,  A23L7/152 ,  A23L25/20

摘要： A method and apparatus for increased yields of water-soluble polyphenols from plant seeds is provided. The method includes inducing seed germination within a selected range of temperatures. The method also includes inducing germination in an atmosphere having elevated carbon oxygen concentration and/or a reduced concentration of oxygen. The method further includes exposing the seeds to light and extracting water-soluble polyphenols with an aqueous solution without adding an organic solvent such as alcohol.

摘要翻译： 提供了一种从植物种子提高水溶性多酚产量的方法和装置。 该方法包括在选定的温度范围内诱导种子发芽。 该方法还包括在具有升高的碳氧浓度和/或降低的氧浓度的气氛中诱导发芽。 该方法还包括将种子暴露于光下，并用水溶液萃取水溶性多酚，而不加入有机溶剂如醇。

公开(公告)号：US20080020113A1

公开(公告)日：2008-01-24

申请号：US11852722

申请日：2007-09-10

申请人： Koji OCHIAI ,  Nobuko Ueda

发明人： Koji OCHIAI ,  Nobuko Ueda

IPC分类号： A23L1/00

CPC分类号： A61K8/97 ,  A61K36/87 ,  A61Q19/00

摘要： To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds. The seeds of grape berries dried after squeezing out the juice are separated into grape seeds and peel with a separation apparatus, and the grape seeds are stirred in a washing machine to remove contamination thoroughly. The grape seeds are charged into a boiling kettle and heated for the prescribed time at the prescribed temperature. Then, germination is induced in a curing kettle maintained at the prescribed temperature preferred for the germination. The grape seeds in which germination or germination and differentiation have advanced are crushed, mixed with water to obtain an emulsified state, and a salt is added, if desired. After a known desalting treatment has been conducted with respect to an aqueous solution portion, water is evaporated with a vacuum apparatus to obtain polyphenols comprising proanthocyanidins converted to a water soluble form.

摘要翻译： 提供一种制造多酚的方法，其可以从葡萄籽中工业制造含有水溶性原花青素的多酚。 榨出果汁后干燥的葡萄浆果的种子被分离成葡萄籽并用分离装置剥离，并将葡萄籽在洗衣机中搅拌以彻底清除污染物。 将葡萄籽装入沸水壶中并在规定温度下加热规定的时间。 然后，在维持在规定温度下用于发芽的固化釜中诱导发芽。 将发芽或发芽和分化进行的葡萄籽粉碎，与水混合以获得乳化状态，如果需要，加入盐。 在对水溶液部分进行已知的脱盐处理之后，用真空装置蒸发水，得到包含转化成水溶性形式的原花色素的多酚。

公开(公告)号：US20080003314A1

公开(公告)日：2008-01-03

申请号：US11603604

申请日：2006-11-21

申请人： Koji Ochiai ,  Nobuko Ueda

发明人： Koji Ochiai ,  Nobuko Ueda

IPC分类号： A61K36/18 ,  A01H3/00

CPC分类号： A23L7/20

摘要： A method and apparatus for increased yields of water-soluble polyphenols from plant seeds is provided. The method includes inducing seed germination within a selected range of temperatures. The method also includes inducing germination in an atmosphere having elevated carbon oxygen concentration and/or a reduced concentration of oxygen. The method further includes exposing the seeds to light and extracting water-soluble polyphenols with an aqueous solution without adding an organic solvent such as alcohol.

摘要翻译： 提供了一种从植物种子提高水溶性多酚产量的方法和装置。 该方法包括在选定的温度范围内诱导种子发芽。 该方法还包括在具有升高的碳氧浓度和/或降低的氧浓度的气氛中诱导发芽。 该方法还包括将种子暴露于光下，并用水溶液萃取水溶性多酚，而不加入有机溶剂如醇。

公开(公告)号：US20060153957A1

公开(公告)日：2006-07-13

申请号：US11246442

申请日：2005-10-06

申请人： Koji Ochiai ,  Nobuko Ueda

发明人： Koji Ochiai ,  Nobuko Ueda

IPC分类号： B02B1/08

CPC分类号： A61K8/97 ,  A61K36/87 ,  A61Q19/00

摘要： [Task] To provide a method for the manufacture of polyphenols that enables industrial manufacture of polyphenols containing water-soluble proanthocyanidins from grape seeds. [Means of solution] The seeds of grape berries dried after squeezing out the juice are separated into grape seeds and peel with a separation apparatus, and the grape seeds are stirred in a washing machine to remove contamination thoroughly. The grape seeds are charged into a boiling kettle and heated for the prescribed time at the prescribed temperature. Then, germination is induced in a curing kettle maintained at the prescribed temperature preferred for the germination. The grape seeds in which germination or germination and differentiation have advanced are crushed, mixed with water to obtain an emulsified state, and a salt is added, if desired. After a known desalting treatment has been conducted with respect to an aqueous solution portion, water is evaporated with a vacuum apparatus to obtain polyphenols comprising proanthocyanidins converted to a water soluble form.

摘要翻译： [任务]提供一种制造多酚的方法，其可以从葡萄籽中工业制造含有水溶性原花青素的多酚。 [解决方法]将挤出果汁后干燥的葡萄浆果种子分离成葡萄籽并用分离装置剥离，并在洗衣机中搅拌葡萄籽以彻底除去污染物。 将葡萄籽装入沸水壶中并在规定温度下加热规定的时间。 然后，在维持在规定温度下用于发芽的固化釜中诱导发芽。 将发芽或发芽和分化进行的葡萄籽粉碎，与水混合以获得乳化状态，如果需要，加入盐。 在对水溶液部分进行已知的脱盐处理之后，用真空装置蒸发水，得到包含转化为水溶性形式的原花色素的多酚。