公开(公告)号：US20170285011A1

公开(公告)日：2017-10-05

申请号：US15151180

申请日：2016-05-10

Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY ,  KOREA BASIC SCIENCE INSTITUTE

Inventor： Du Woon KIM ,  Joseph KWON

IPC: G01N33/50 ,  G01N33/569 ,  A61K38/16

CPC classification number: G01N33/5088 ,  A61K38/168 ,  C12Q1/68 ,  G01N33/5091 ,  G01N33/56983 ,  G01N2333/08 ,  G01N2333/4603 ,  Y02A50/463

Abstract: Discloses are a method for detecting Norovirus using a Norovirus animal model, a method for screening an antivial agent against Norovirus, and a composition for neutralizing the infection with an enteric virus, containing concanavalin A as an active ingredient, so that the method for detecting Norovirus can allow the distinction between infectious Norovirus and non-infectious Norovirus, and the composition can neutralize a virus causing food poisoning.

公开(公告)号：US20170067911A1

公开(公告)日：2017-03-09

申请号：US15339773

申请日：2016-10-31

Applicant: Korea Basic Science Institute

Inventor： Ik Soon JANG ,  Jong Soon CHOI ,  Joseph KWON ,  Dong-Gi LEE ,  Kyeong Eun YANG

IPC: G01N33/68 ,  C07K16/18

CPC classification number: G01N33/6887 ,  C07K16/18 ,  G01N2333/82

Abstract: The present invention relates to a beef-specific age determination marker containing the p21 protein, to an antibody specifically bound to bovine p21 protein, to a beef-specific age determination kit containing the antibody which is specifically bound to the bovine p21 protein, and to a method which involves detecting the bovine p21 protein through an antigen-antibody binding reaction using the antibody which is specifically bound to the bovine p21 protein serving as a beef-specific age determination marker in the muscle tissue of beef, so as to determine the age of the beef. According to the present invention, the p21 protein is significantly greatly expressed in the muscle tissue of beef, the age of which is lower than 30 months, and is hardly expressed in the muscle tissue of beef, the age of which is greater than 30 months, and thus can be valuably used as a beef-specific age determination marker.

Abstract translation: 本发明涉及含有p21蛋白的牛肉特异性年龄测定标记与特异性结合牛p21蛋白的抗体相关的牛肉特异性年龄测定试剂盒，其含有与牛p21蛋白特异性结合的抗体，以及 一种方法，其涉及通过抗原 - 抗体结合反应检测牛p21蛋白的方法，其使用特异性结合牛肉肌肉组织中牛肉特异性年龄测定标记的牛p21蛋白特异性结合的抗体，以确定年龄 的牛肉。 根据本发明，p21蛋白在牛肉肌肉组织中的表达显着高于30个月，几乎不能在牛肉的肌肉组织中表达，其年龄大于30个月 ，因此可以有价值地用作牛肉特异性年龄确定标记。