公开(公告)号：US20180370922A1

公开(公告)日：2018-12-27

申请号：US16015596

申请日：2018-06-22

Applicant: Korea Institute of Science and Technology

Inventor： Eun Joo ROH ,  Karam Mohamed Hasan Fara AHMED ,  So Ra PAIK ,  Woo Young HUR ,  Elkamhawy AHMED

IPC: C07D239/48 ,  C07D413/12 ,  A61P19/02 ,  A61P1/00

Abstract: The present invention relates to a 6-phenoxypyrimidine derivative, a method for preparing the compound and a pharmaceutical composition containing the compound as an active ingredient. Because the 6-phenoxypyrimidine compound represented by Chemical Formula 1 according to the present invention has an activity of inhibiting the production of nitric oxide (NO) as an inflammation-related factor, it is useful in treating and preventing inflammatory diseases including immunological diseases.