公开(公告)号：US20240216428A1

公开(公告)日：2024-07-04

申请号：US18288815

申请日：2022-04-27

Applicant: Korea Research Institute of Bioscience and Biotechnology

Inventor： Tae-Don KIM ,  Seona CHO ,  Sooyun LEE

IPC: A61K35/17 ,  A61K39/00 ,  A61P35/02 ,  C07K14/725 ,  C07K16/28 ,  C12N15/86

CPC classification number: A61K35/17 ,  A61K39/4613 ,  A61P35/02 ,  C07K14/7051 ,  C07K16/2896 ,  C12N15/86 ,  A61K2239/13 ,  C07K2317/622 ,  C07K2319/02 ,  C07K2319/03 ,  C12N2740/15043

Abstract: The present invention relates to a CD5 antibody and a chimeric antigen receptor (CAR) including the same. The chimeric antigen receptor of the present invention may be expressed in an immune cell to be utilized for an immuno-oncology therapy having reduced toxicity against a normal T cell.