利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

2 条记录 (耗时 0.013 秒)

    Substituted 1,3-dialkylpyrido[4,3-d]pyrimidine-2,4-diones
    1.
    发明授权
    Substituted 1,3-dialkylpyrido[4,3-d]pyrimidine-2,4-diones 失效
    取代的1,3-二烷基吡啶并[4,3-d]嘧啶-2,4-二酮

    公开(公告)号：US4808618A

    公开(公告)日：1989-02-28

    申请号：US35797

    申请日：1987-04-08

    申请人： Kouichiro Go ,  Yoshiyuki Kurimoto ,  Norihiko Kitamura

    发明人： Kouichiro Go ,  Yoshiyuki Kurimoto ,  Norihiko Kitamura

    IPC分类号： A61K31/505 ,  A61P37/08 ,  C07D471/04

    CPC分类号： C07D471/04

    摘要： The present invention relates to a novel pyrido[4,3-d]pyrimidine derivative having the formula (I): ##STR1## wherein each of R.sub.1 and R.sub.2, which may be the same or different, is a lower alkyl group; R.sub.3 is hydrogen, halogen, hydroxy, amino, hydroxyamino, imino, hydrazino or a lower alkylamino group which may optionally have hydroxy, amino or a lower alkylamino group; and R.sub.4 is hydrogen, amino, --NH.sup..crclbar. or a lower alkyl group which may optionally have hydroxy, amino or a lower alkylamino group; and pharmaceutically acceptable salt thereof. These compounds are useful as anti-allergic agents, for example, for the treatment of bronchial asthma, urticaria, allergic rhinitis, allergic dermatoses or allergic conjunctivitis.

    摘要翻译： 本发明涉及具有式（I）的新颖的吡啶并[4,3-d]嘧啶衍生物：其中R1和R2可以相同或不同，为低级烷基 ; R 3是氢，卤素，羟基，氨基，羟基氨基，亚氨基，肼基或可任选具有羟基，氨基或低级烷基氨基的低级烷基氨基; 和R 4是氢，氨基，-NH（ - ）或可任选具有羟基，氨基或低级烷基氨基的低级烷基; 及其药学上可接受的盐。 这些化合物可用作抗过敏剂，例如用于治疗支气管哮喘，荨麻疹，过敏性鼻炎，过敏性皮肤病或过敏性结膜炎。

    5-substituted pyrido[2,3-d]pyrimidine-2,4-diones
    2.
    发明授权
    5-substituted pyrido[2,3-d]pyrimidine-2,4-diones 失效
    5-取代的吡啶并[2,3-d]嘧啶-2,4-二酮

    公开(公告)号：US4808587A

    公开(公告)日：1989-02-28

    申请号：US35798

    申请日：1987-04-08

    申请人： Kouichiro Go ,  Yoshiyuki Kurimoto ,  Norihiko Kitamura

    发明人： Kouichiro Go ,  Yoshiyuki Kurimoto ,  Norihiko Kitamura

    IPC分类号： A61K31/505 ,  A61P37/08 ,  C07D471/04

    CPC分类号： C07D471/04

    摘要： The present invention relates to a novel pyrido[2,3-d]pyrimidine derivative having the formula (I): ##STR1## wherein each of R.sub.1 and R.sub.2, which may be the same or different, is a lower alkyl group; and each of R.sub.3 and R.sub.4, which may be the same or different, is hydrogen, halogen, hydroxy, nitro, amino, hydroxyamino, hydrazino, azido, a lower alkenylamino group or a lower alkylamino group which may optionally have hydroxy; and pharmaceutically acceptable salt thereof. These compounds are useful as anti-allergic agents, for example, for the treatment of bronchial asthma, urticaria, allergic rhinitis, allergic dermatoses or allergic conjunctivitis.

    摘要翻译： 本发明涉及具有式（I）的新颖的吡啶并[2,3-d]嘧啶衍生物：其中R1和R2可以相同或不同，为低级烷基 ; 可以相同或不同的R 3和R 4可以是氢，卤素，羟基，硝基，氨基，羟基氨基，肼基，叠氮基，低级链烯基氨基或可以具有羟基的低级烷基氨基; 及其药学上可接受的盐。 这些化合物可用作抗过敏剂，例如用于治疗支气管哮喘，荨麻疹，过敏性鼻炎，过敏性皮肤病或过敏性结膜炎。