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    METHOD OF AND SOFTWARE FOR CALCULATING A SCATTER ESTIMATE FOR TOMOGRAPHIC SCANNING AND SYSTEM FOR TOMOGRAPHIC SCANNING
    3.
    发明申请
    METHOD OF AND SOFTWARE FOR CALCULATING A SCATTER ESTIMATE FOR TOMOGRAPHIC SCANNING AND SYSTEM FOR TOMOGRAPHIC SCANNING 失效
    计算用于TOMOGRAPHIC扫描的散射估计的方法和软件以及用于TOMOGRAPHIC扫描的系统

    公开(公告)号：US20100086101A1

    公开(公告)日：2010-04-08

    申请号：US12518334

    申请日：2007-12-18

    申请人： Kris Filip Johan Jules Thielemans ,  Charalampos Panos Tsoumpas ,  Floribertus P. M. Heukensfeldt Jansen

    发明人： Kris Filip Johan Jules Thielemans ,  Charalampos Panos Tsoumpas ,  Floribertus P. M. Heukensfeldt Jansen

    IPC分类号： H05G1/60 ,  G06K9/00

    CPC分类号： G01T1/1647 ,  G06T11/005

    摘要： The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps: determine an estimate of the unscattered events; determine a simulation of the scattered events; determine a value of a scaling factor by fitting the sum of the estimate of the unscattered events and a product of the scaling factor and the simulation of the scattered events to the detection data; and determine the scatter estimate as the product of the scaling factor having said value and the simulation of the scattered events.

    摘要翻译： 该方法计算用于正电子发射断层摄影扫描仪中来自被摄体的检测数据的散射校正的散射估计。 检测数据表示在受试者中发射的湮灭光子的分散事件和不受散射的事件。 该方法使用以下步骤：确定未分散事件的估计; 确定分散事件的模拟; 通过将未散射事件的估计和缩放因子的乘积和分散事件的模拟的和拟合到检测数据来确定缩放因子的值; 并将散射估计确定为具有所述值的缩放因子与散射事件的模拟的乘积。

    Method of and software for calculating a scatter estimate for tomographic scanning and system for tomographic scanning
    4.
    发明授权
    Method of and software for calculating a scatter estimate for tomographic scanning and system for tomographic scanning 失效
    用于计算层析扫描的散射估计的方法和软件以及用于层析扫描的系统

    公开(公告)号：US07902511B2

    公开(公告)日：2011-03-08

    申请号：US12518334

    申请日：2007-12-18

    申请人： Kris Filip Johan Jules Thielemans ,  Charalampos Panos Tsoumpas ,  Floribertus P. M. Heukensfeldt Jansen

    发明人： Kris Filip Johan Jules Thielemans ,  Charalampos Panos Tsoumpas ,  Floribertus P. M. Heukensfeldt Jansen

    IPC分类号： G01T1/164

    CPC分类号： G01T1/1647 ,  G06T11/005

    摘要： The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps: determine an estimate of the unscattered events; determine a simulation of the scattered events; determine a value of a scaling factor by fitting the sum of the estimate of the unscattered events and a product of the scaling factor and the simulation of the scattered events to the detection data; and determine the scatter estimate as the product of the scaling factor having said value and the simulation of the scattered events.

    摘要翻译： 该方法计算用于正电子发射断层摄影扫描仪中来自被摄体的检测数据的散射校正的散射估计。 检测数据表示在受试者中发射的湮灭光子的分散事件和不受散射的事件。 该方法使用以下步骤：确定未分散事件的估计; 确定分散事件的模拟; 通过将未散射事件的估计和缩放因子的乘积和分散事件的模拟的和拟合到检测数据来确定缩放因子的值; 并将散射估计确定为具有所述值的缩放因子与散射事件的模拟的乘积。

    Method and system for calibrating a time of flight positron emission tomography system
    5.
    发明授权
    Method and system for calibrating a time of flight positron emission tomography system 失效
    校准飞行时间正电子发射断层扫描系统的方法和系统

    公开(公告)号：US07345281B2

    公开(公告)日：2008-03-18

    申请号：US11786951

    申请日：2007-04-13

    申请人： Floribertus P. M. Heukensfeldt Jansen ,  Ravindra Mohan Manjeshwar

    发明人： Floribertus P. M. Heukensfeldt Jansen ,  Ravindra Mohan Manjeshwar

    IPC分类号： G01T1/161

    CPC分类号： G01T1/2985

    摘要： A method and system for calibrating a time of flight (TOF) positron emission tomography (PET) scanner are provided. The method stores acquired scan data from detector pairs including data and timing information. The method further calculates an intensity distribution of emission sources based on the scan data and defines a timing pivot point based on a median of an intensity histogram. The method determines a timing correction for each detector based on the location of the timing pivot point. The positron emission tomography (PET) system further provides a plurality of detectors, used in performing imaging scans, and a processor. The processor is configured to determine a timing correction for each detector.

    摘要翻译： 提供了一种用于校准飞行时间（TOF）正电子发射断层摄影（PET）扫描仪的方法和系统。 该方法存储来自检测器对的获取的扫描数据，包括数据和定时信息。 该方法还基于扫描数据计算发射源的强度分布，并且基于强度直方图的中值来定义定时枢轴点。 该方法基于定时枢轴点的位置确定每个检测器的定时校正。 正电子发射断层摄影（PET）系统还提供用于执行成像扫描的多个检测器和处理器。 处理器被配置为确定每个检测器的定时校正。

    Method and system for calibrating a time of flight positron emission tomography system
    6.
    发明授权
    Method and system for calibrating a time of flight positron emission tomography system 有权
    校准飞行时间正电子发射断层扫描系统的方法和系统

    公开(公告)号：US07211799B2

    公开(公告)日：2007-05-01

    申请号：US11226171

    申请日：2005-09-14

    申请人： Floribertus P. M. Heukensfeldt Jansen ,  Ravindra Mohan Manjeshwar

    发明人： Floribertus P. M. Heukensfeldt Jansen ,  Ravindra Mohan Manjeshwar

    IPC分类号： G01T1/161

    CPC分类号： G01T1/2985

    摘要： A method and system for calibrating a Time of Flight Positron Emission Tomography (TOF PET) system are provided. The method includes storing acquired scan data from detector pairs. The acquired scan data includes image data and timing information. The method further includes reconstructing images using scan data. The method also includes determining a timing correction for each detector based on intensity distribution histograms of emission sources. The system includes a controller, which is configured to perform the above-mentioned method steps.

    摘要翻译： 提供了一种用于校准飞行时间正电子发射断层扫描（TOF PET）系统的方法和系统。 该方法包括从检测器对存储获取的扫描数据。 获取的扫描数据包括图像数据和定时信息。 该方法还包括使用扫描数据重建图像。 该方法还包括基于发射源的强度分布直方图确定每个检测器的定时校正。 该系统包括控制器，其被配置为执行上述方法步骤。

    Apparatus and method for image reconstruction for a synthetic aperture gamma ray imager
    7.
    发明授权
    Apparatus and method for image reconstruction for a synthetic aperture gamma ray imager 有权
    用于合成孔径伽马射线成像仪的图像重建的装置和方法

    公开(公告)号：US07663105B2

    公开(公告)日：2010-02-16

    申请号：US12331936

    申请日：2008-12-10

    申请人： Ralph Thomas Hoctor ,  Scott Stephen Zelakiewicz ,  Evren Asma ,  Jeffrey Gordon ,  Floribertus P. M. Heukensfeldt Jansen

    发明人： Ralph Thomas Hoctor ,  Scott Stephen Zelakiewicz ,  Evren Asma ,  Jeffrey Gordon ,  Floribertus P. M. Heukensfeldt Jansen

    IPC分类号： G01T1/00

    CPC分类号： G03B42/02

    摘要： An imaging system includes a platform having mounted thereon a coded-aperture imaging device and positioned to receive radiation over a baseline. The imaging system includes a computer configured to acquire a plurality of far-field datasets over the baseline, the plurality of far-field datasets comprising data received via the coded-aperture imaging device. The computer is also configured to form a preliminary image based on the acquired plurality of far-field datasets, and apply an expectation maximization (EM) algorithm to the preliminary image; wherein the EM algorithm includes an ordered subset algorithm.

    摘要翻译： 成像系统包括其上安装有编码孔径成像装置并被定位成在基线上接收辐射的平台。 成像系统包括被配置为在基线上获取多个远场数据集的计算机，所述多个远场数据集包括经由编码孔径成像装置接收的数据。 计算机还被配置为基于所获取的多个远场数据集形成初步图像，并将预期最大化（EM）算法应用于初步图像; 其中所述EM算法包括有序子集算法。

    Method and system for non-invasive imaging of a target region
    8.
    发明授权
    Method and system for non-invasive imaging of a target region 有权
    目标区域非侵入性成像的方法和系统

    公开(公告)号：US09237874B2

    公开(公告)日：2016-01-19

    申请号：US13459585

    申请日：2012-04-30

    申请人： Bruno Kristiaan Bernard DeMan ,  James Vradenburg Miller ,  Floribertus P. M. Heukensfeldt Jansen

    发明人： Bruno Kristiaan Bernard DeMan ,  James Vradenburg Miller ,  Floribertus P. M. Heukensfeldt Jansen

    IPC分类号： G01T1/161 ,  A61B6/03 ,  G06T11/00 ,  A61B6/12 ,  A61B6/00 ,  A61B6/06

    CPC分类号： A61B6/032 ,  A61B6/037 ,  A61B6/06 ,  A61B6/12 ,  A61B6/4021 ,  A61B6/4241 ,  A61B6/4417 ,  A61B6/469 ,  A61B6/482 ,  A61B6/488 ,  G06T11/005

    摘要： Embodiments of systems, methods and non-transitory computer readable media for imaging are presented. Preliminary image data corresponding to a first FOV of a subject at a first resolution is acquired using an imaging system including one or more radiation sources and at least one hybrid detector, specifically using at least one section of the hybrid detector having the first resolution. The target ROI is identified using the preliminary image data. Further, the subject is positioned to align the target ROI along a designated axis. Additionally, parameters associated with the sources, the hybrid detector and/or an imaging system gantry are configured for acquiring target image data at a second resolution greater than the first resolution using at least one section of the hybrid detector having the second resolution. Further, one or more images corresponding to at least the target ROI are reconstructed using the target and/or the preliminary image data.

    摘要翻译： 提出了用于成像的系统，方法和非暂时计算机可读介质的实施例。 使用包括一个或多个辐射源和至少一个混合检测器的成像系统，特别是使用具有第一分辨率的混合检测器的至少一个部分，获取与第一分辨率的对象的第一FOV相对应的初步图像数据。 使用初步图像数据来识别目标ROI。 此外，被摄体被定位成沿着指定轴对准目标ROI。 另外，与源相关联的参数，混合检测器和/或成像系统台架被配置为使用具有第二分辨率的混合检测器的至少一个部分以大于第一分辨率的第二分辨率来获取目标图像数据。 此外，使用目标和/或初步图像数据来重构与至少目标ROI相对应的一个或多个图像。

    Gamma camera stabilizer
    9.
    发明授权
    Gamma camera stabilizer 失效
    伽玛相机稳定器

    公开(公告)号：US6008494A

    公开(公告)日：1999-12-28

    申请号：US1568

    申请日：1997-12-31

    申请人： Floribertus P. M. Heukensfeldt Jansen

    发明人： Floribertus P. M. Heukensfeldt Jansen

    IPC分类号： G01T1/164 ,  G01T1/161

    CPC分类号： G01T1/1648

    摘要： An apparatus and method to be used with a gamma camera for identifying and compensating for photomultiplier tube gain drift wherein a photon source is used during a customer quality control flood procedure to direct photons toward the camera and wherein the source is known to generate approximately identical numbers of photons at energies within an acquisition range of energy levels, the acquisition range having a mid-value at energy level Z, the camera is used to generate an upper image using photons having energies above level Z and within the acquisition range and to generate a lower image using photons having energies below level Z and within the acquisition range, the upper and lower images are used to identify PMTs with incorrect gain, identify gain error and then compensate for the error.

    摘要翻译： 一种与γ照相机一起使用以识别和补偿光电倍增管增益漂移的装置和方法，其中在客户质量控制泛洪过程期间使用光子源以将光子引向照相机，并且其中已知源产生大致相同的数字 在能量级的采集范围内的能量的光子中，采集范围具有在能级Z的中间值，照相机用于使用具有高于等级Z的能量并且在获取范围内的光子产生上部图像，并且生成 使用能量低于等级Z并且在采集范围内的光子的较低图像，上下图像用于识别具有不正确增益的PMT，识别增益误差，然后补偿误差。

    Adjustable-focal-length collimators method and system
    10.
    发明授权
    Adjustable-focal-length collimators method and system 有权
    可调焦距准直器的方法和系统

    公开(公告)号：US07671340B2

    公开(公告)日：2010-03-02

    申请号：US11778290

    申请日：2007-07-16

    申请人： Jorge Uribe ,  Floribertus P. M. Heukensfeldt Jansen ,  James William Hugg

    发明人： Jorge Uribe ,  Floribertus P. M. Heukensfeldt Jansen ,  James William Hugg

    IPC分类号： G21K1/02

    CPC分类号： A61B6/06 ,  A61B6/037

    摘要： Embodiments relate to an imaging system that includes a collimator assembly having one or more pinhole apertures therein. The imaging system is configured so that one or more of the pinhole apertures has an adjustable focal length. The imaging system further includes a detector assembly configured to generate one or more signals in response to gamma rays that pass through the one or more pinhole apertures. Embodiments also relate to methods of changing collimator performance and methods of imaging a volume.

    摘要翻译： 实施例涉及一种成像系统，其包括其中具有一个或多个针孔的准直器组件。 成像系统被配置为使得一个或多个针孔具有可调整的焦距。 成像系统还包括检测器组件，其被配置为响应于穿过所述一个或多个针孔的伽马射线产生一个或多个信号。 实施例还涉及改变准直器性能的方法和对体积进行成像的方法。