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公开(公告)号：US20200010807A1
公开(公告)日：2020-01-09
申请号：US16461905
申请日：2017-11-21
Applicant: Kyoto University
Inventor： Kenji OSAFUNE , Satoshi MATSUI
IPC: C12N5/071
Abstract: Provided are: a method for producing biliary epithelial progenitor cells, said method comprising a step for culturing hepatoblasts in a medium containing TGFβ and EGF; and a method for constructing a three-dimensional duct-like structure of biliary epithelial progenitor cells, said method comprising a step for culturing hepatoblasts or biliary epithelial progenitor cells in a medium containing HGF, EGF, a Notch inhibitor and a GSK3 inhibitor in the presence of a three-dimensional scaffold material.
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