公开(公告)号：US09278974B2

公开(公告)日：2016-03-08

申请号：US14442816

申请日：2013-11-14

Applicant: LABORATORIOS DEL DR. ESTEVE S.A.

Inventor： José Luis Díaz Fernández ,  Carme Almansa ,  Jordi Corbera Arjona

IPC: C07D293/06 ,  C07H21/00 ,  C07D487/04

CPC classification number: C07D487/04

Abstract: The present invention relates to new substituted pyrazolo[3,4-d]pyrimidine compounds, having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.

Abstract translation: 本发明涉及对σ受体，特别是σ-1受体以及其制备方法对包含它们的组合物具有很大亲和性的新的取代的吡唑并[3,4-d]嘧啶化合物， 用作药物。