Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs
    1.
    发明申请
    Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs 审中-公开
    肉毒杆菌神经毒素血清型B可活化肉毒杆菌神经毒素血清型Bs

    公开(公告)号:US20110111479A1

    公开(公告)日:2011-05-12

    申请号:US12871585

    申请日:2010-08-30

    IPC分类号: C12N9/48 C07H21/04

    CPC分类号: C07K14/33

    摘要: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.

    摘要翻译: 该说明书公开了修饰的梭菌毒素,其包含位于二链环区内的梭菌毒素底物切割位点; 编码这种经修饰的梭菌毒素的多核苷酸分子,其包含位于二链环区域中的梭菌毒素底物切割位点; 以及产生修饰梭菌毒素的方法,其包含位于二链环区内的梭菌毒素底物切割位点。

    Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs
    2.
    发明申请
    Botulinum Neurotoxin Serotype B Activatable Botulinum Neurotoxin Serotype Bs 审中-公开
    肉毒杆菌神经毒素血清型B可活化肉毒杆菌神经毒素血清型Bs

    公开(公告)号:US20120115205A1

    公开(公告)日:2012-05-10

    申请号:US12871486

    申请日:2010-08-30

    IPC分类号: C12N9/52 C12N15/57

    CPC分类号: C07K14/33

    摘要: The specification discloses modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins comprising a Clostridial toxin substrate cleavage site located in the di-chain loop region; and method of producing modified Clostridial toxins comprising Clostridial toxin substrate cleavage site located within the di-chain loop region.

    摘要翻译: 该说明书公开了修饰的梭菌毒素,其包含位于二链环区内的梭菌毒素底物切割位点; 编码这种经修饰的梭菌毒素的多核苷酸分子,其包含位于二链环区域中的梭菌毒素底物切割位点; 以及产生修饰梭菌毒素的方法,其包含位于二链环区内的梭菌毒素底物切割位点。