公开(公告)号：US11345747B2

公开(公告)日：2022-05-31

申请号：US16700471

申请日：2019-12-02

申请人： LANKENAU INSTITUTE FOR MEDICAL RESEARCH

发明人： Thomas Sunil ,  James Mullin ,  George C. Prendergast

IPC分类号： A61K39/395 ,  A61K45/06 ,  A61K39/00 ,  C07K16/18 ,  A61P37/00

摘要： Compositions and methods for the treatment of a disease or disorder are disclosed. Specifically, methods for inhibiting, treating, and/or preventing inflammatory disease in patients in need thereof are provided. The methods comprise the administration of at least one antibody or antibody fragment immunologically specific for bridging integrator I (Bin 1), particularly the Myc binding domain.

公开(公告)号：US20200157199A1

公开(公告)日：2020-05-21

申请号：US16700471

申请日：2019-12-02

申请人： LANKENAU INSTITUTE FOR MEDICAL RESEARCH

发明人： Thomas Sunil ,  James Mullin ,  George C. Prendergast

IPC分类号： C07K16/18 ,  A61K39/395 ,  A61K45/06

摘要： Compositions and methods for the treatment of a disease or disorder are disclosed. Specifically, methods for inhibiting, treating, and/or preventing inflammatory disease in patients in need thereof are provided. The methods comprise the administration of at least one antibody or antibody fragment immunologically specific for bridging integrator I (Bin 1), particularly the Myc binding domain.