专利检索 ap:("LAWRENCE LIVERMORE NATIONAL SECURITY, LLC") AND inv:"Martina Felderman" 第 1 页

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发明授权
Nanolipoprotein particles and related compositions methods and systems for loading RNA 有权

公开(公告)号：US12083223B2

公开(公告)日：2024-09-10

申请号：US15969311

申请日：2018-05-02

申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

发明人： Kurt I. Kamrud , Nathaniel S. Wang , Martina Felderman , Bolyn Hubby , Heather D. Gouvis , Nicholas O. Fischer , Matthew A. Coleman , Angela Clare Evans , Wei He , Amy Rasley , Craig D. Blanchette

IPC分类号： A61K9/127 , A61K47/69 , A61K48/00 , C12N15/88

CPC分类号： A61K9/1272 , A61K9/1274 , A61K47/6917 , C12N15/88 , A61K48/0008

摘要： Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related complexes, compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more cationic lipids.