公开(公告)号：US11377425B1

公开(公告)日：2022-07-05

申请号：US16765143

申请日：2019-12-19

Applicant: LEO Pharma A/S

Inventor： Kevin Neil Dack ,  Xifu Liang ,  Mogens Larsen ,  Mark Andrews ,  Alan Stuart Jessiman ,  Mia Nørreskov Burhardt ,  Patrick Stephen Johnson ,  Peter Andersen ,  Lars Jørgensen

IPC: C07D231/12 ,  C07D403/12 ,  C07D249/06 ,  C07D271/10 ,  C07D263/32 ,  C07D413/12 ,  C07D233/64 ,  C07D231/14 ,  C07D233/68 ,  C07D233/70 ,  C07D261/08

Abstract: The present invention relates to a compound according to formula I and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

公开(公告)号：US12065429B2

公开(公告)日：2024-08-20

申请号：US18526149

申请日：2023-12-01

Applicant: LEO Pharma A/S

Inventor： Mark Andrews ,  Mogens Larsen ,  Alan Jessiman ,  Patrick Johnson ,  Kevin Neil Dack

IPC: C07D401/14

CPC classification number: C07D401/14

Abstract: The present invention relates to a compound according to formula (I)




and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g., dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.