Patent search ap:("LEO Pharma A/S") AND inv:"Xifu Liang" Page 1

1.

发明授权
Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors 有权

公开(公告)号：US10793580B2

公开(公告)日：2020-10-06

申请号：US16468429

申请日：2016-12-12

Applicant: LEO Pharma A/S

Inventor： Xifu Liang , Jens Larsen

IPC: C07D491/20

Abstract: The present invention relates to novel pyrazoloazepin-8-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.

2.

发明授权
Small molecule modulators of IL-17 有权

公开(公告)号：US11377425B1

公开(公告)日：2022-07-05

申请号：US16765143

申请日：2019-12-19

Applicant: LEO Pharma A/S

Inventor： Kevin Neil Dack , Xifu Liang , Mogens Larsen , Mark Andrews , Alan Stuart Jessiman , Mia Nørreskov Burhardt , Patrick Stephen Johnson , Peter Andersen , Lars Jørgensen

IPC: C07D231/12 , C07D403/12 , C07D249/06 , C07D271/10 , C07D263/32 , C07D413/12 , C07D233/64 , C07D231/14 , C07D233/68 , C07D233/70 , C07D261/08

Abstract: The present invention relates to a compound according to formula I and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

3.

发明授权
Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 有权

公开(公告)号：US11065257B2

公开(公告)日：2021-07-20

申请号：US16468444

申请日：2017-12-12

Applicant: LEO Pharma A/S

Inventor： Xifu Liang , Jens Larsen , Simon Feldbaek Nielsen , Peter Andersen

IPC: C07D491/20 , A61K31/55

Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.

4.

发明授权
Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 有权

公开(公告)号：US10906915B2

公开(公告)日：2021-02-02

申请号：US16468420

申请日：2016-12-12

Applicant: LEO Pharma A/S

Inventor： Xifu Liang , Jens Larsen , Simon Feldbaek Nielsen , Peter Andersen

IPC: C07D491/20

Abstract: The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.

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