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1.
公开(公告)号:US20180273528A1
公开(公告)日:2018-09-27
申请号:US15763248
申请日:2016-09-30
发明人: Balázs BÁLINT , András KOTSCHY , Melinda SIPOS , Csaba WÉBER , Nicolas FOLOPPE , David WALMSLEY , Michael BURBRIDGE , Francisco Humberto CRUZALEGUI
IPC分类号: C07D471/04 , A61K31/444 , A61K45/06 , A61P35/00
CPC分类号: C07D471/04 , A61K31/444 , A61K45/06 , A61P35/00
摘要: Compounds of formula (I): wherein R1, R2, R3, R4, and R5 are as defined in the description.Medicinal products containing the same which are useful in treating cancer, neurodegenerative disorders and metabolic disorders.
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公开(公告)号:US20210355106A1
公开(公告)日:2021-11-18
申请号:US17282898
申请日:2019-10-18
发明人: Csaba WÉBER , András KOTSCHY , Attila VASAS , Árpád KISS , Balázs MOLNÁR , Andrea FIUMANA , Alba MACIAS , James Brooke MURRAY , Didier DEMARLES , Lisa IVANSCHITZ , Olivier GENESTE , Kristóf HEGEDÜS , Péter SPRÁNITZ , Tibor SOÓS
IPC分类号: C07D401/14 , A61P35/00 , A61K45/06 , A61K31/513 , C07D417/14 , A61K31/517 , C07D409/14 , C07D405/14
摘要: wherein R1, R2, R3, R4, R5, n and Q are as defined in the description.
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公开(公告)号:US20190144449A1
公开(公告)日:2019-05-16
申请号:US16306941
申请日:2017-06-09
发明人: András KOTSCHY , Csaba WÉBER , Attila VASAS , Balázs MOLNÁR , Árpád KISS , Alba MACIAS , James Brooke MURRAY , Elodie LEWKOWICZ , Olivier GENESTE , Maïa CHANRION , Didier DEMARLES , Lisa IVANSCHITZ
IPC分类号: C07D471/04 , A61P35/00 , C07D487/04 , C07D495/04 , A61K31/519 , A61K31/522
摘要: Compounds of formula (I): wherein R1, R2, J, K, L, n and W are as defined in the description.Medicinal products containing the same which are useful in treating conditions requiring pro-apoptotic and/or anti-proliferative agents.
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4.
公开(公告)号:US20190144448A1
公开(公告)日:2019-05-16
申请号:US16306933
申请日:2017-06-09
发明人: András KOTSCHY , Csaba WÉBER , Attila VASAS , Balázs MOLNÁR , Árpád KISS , Alba MACIAS , James Brooke MURRAY , Elodie LEWKOWICZ , Olivier GENESTE , Maïa CHANRION , Didier DEMARLES
IPC分类号: C07D471/04 , A61P35/00 , C07D487/04 , A61P37/02
摘要: Compounds of formula (I): wherein R1, R2, R3, n and W are as defined in the description.Medicinal products containing the same which are useful in treating conditions requiring pro-apoptotic and/or anti-proliferative agents.
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公开(公告)号:US20210221785A1
公开(公告)日:2021-07-22
申请号:US17254482
申请日:2019-07-04
发明人: Csaba WÉBER , András KOTSCHY , Attila VASAS , Árpád KISS , Balázs MOLNÁR , Alba MACIAS , Andrea FIUMANA , Nicolas DAVIES , James Brooke MURRAY , Emilie SELLIER , Didier DEMARLES , Lisa IVANSCHITZ , Olivier GENESTE
IPC分类号: C07D401/06 , C07D401/14 , A61K35/17 , A61K45/06 , A61K31/506
摘要: Compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, J and n are as defined in the description.
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公开(公告)号:US20230097678A1
公开(公告)日:2023-03-30
申请号:US17904514
申请日:2021-02-26
发明人: Csaba WÉBER , Klaus SEEDORF , Didier DURAND , Márió GYURIS , Árpád KISS , Zoltán MADARÁSZ , Mark MOLNÁR , Miklós NYERGES , Monika RUDASOVÁ , Attila SÁPI , Sylvie BERGER , Valérie DUVIVIER , Virginie MARTINY , Isabelle THERET , Cédric VINSON
IPC分类号: A61K31/547 , C07D515/18 , A61K9/20 , A61P1/16 , A61P3/10
摘要: A compound of formula (I): wherein Z, Y1, Y2, R1 to R7 are as defined in the description, its optical isomers, and addition salts thereof with a pharmaceutically acceptable base.
Medicaments.
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