公开(公告)号：US20230410943A1

公开(公告)日：2023-12-21

申请号：US18143828

申请日：2023-05-05

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Cheng-Zong Bai ,  Eugene Ingerman ,  Chao Wang ,  Alison Lai ,  Werner Puschitz

IPC: G16B20/20 ,  G06N3/0464 ,  G06N3/09 ,  G16B30/00 ,  G16B40/20

CPC classification number: G16B20/20 ,  G06N3/0464 ,  G06N3/09 ,  G16B30/00 ,  G16B40/20

Abstract: A method for labeling sequence reads includes retrieving a sequence read having an associated flow measurement and an associated flow order; matching a sequence selected from a plurality of sequences with the sequence read, the sequence having a position within the sequence that has more than one acceptable variants; determining which variant of the more than one acceptable variants matches the sequence; generating a predicted flow measurement based on the matched sequence, the variant, and a flow order; and labeling the sequence read and associated flow measurement with the predicted flow measurement.