公开(公告)号：US20240409839A1

公开(公告)日：2024-12-12

申请号：US18248381

申请日：2023-03-02

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： LEE SPEIGHT ,  ANDREW MORRIS ,  DANIEL HAGAMAN

IPC: C10M145/40 ,  C09K23/56 ,  C10N40/20 ,  C10N50/00 ,  C10N70/00

Abstract: The subject invention provides biological emulsifying agents for use in formulating metalworking fluids, methods for formulating the metalworking fluids, and enhanced metalworking fluids.

公开(公告)号：US20250000986A1

公开(公告)日：2025-01-02

申请号：US18249245

申请日：2023-02-01

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： SEAN FARMER ,  LEE SPEIGHT ,  DANIEL HAGAMAN ,  ANDREW MORRIS ,  NICHOLAS CALLOW

IPC: A61K47/54

Abstract: The present invention provides modified sophorolipids of formula (I) incorporating therapeutic molecules as therapeutic agent cargos to improve the bioavailability and/or delivery of such agents. The modified sophorolipids of the present invention are capable of efficiently delivering the therapeutic agent cargos to the target site and enhancing the efficacy of the therapeutic agent cargos and/or the sophorolipids. Additionally, the present invention provides methods of treating skin conditions or ailments as well as of maintaining or restoring gut health in a subject.

公开(公告)号：US20240407992A1

公开(公告)日：2024-12-12

申请号：US18249246

申请日：2023-02-28

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： LEE SPEIGHT ,  DANIEL HAGAMAN ,  ANDREW MORRIS ,  AYENDA ZEMAITIS

IPC: A61K8/60 ,  A61Q5/12 ,  C11D1/58

Abstract: The subject invention provides conditioning compositions for hair, fibers and textiles, wherein the conditioning compositions comprise derivatized cationic biosurfactants.

公开(公告)号：US20250129401A1

公开(公告)日：2025-04-24

申请号：US18268373

申请日：2023-06-07

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： LEE SPEIGHT ,  DANIEL HAGAMAN ,  ANDREW MORRIS

IPC: C12P19/44 ,  C07H15/00

Abstract: The present invention provides modified sophorolipids of formula (I) that are more pH-and temperature-stable than its lactonic counterparts. Moreover, the compound has reduced HLB parameters, as well as improved wetting and solubilization parameters, water-in-oil emulsification ability, surface tension-lowering activity, and/or antimicrobial activity compared to their acidic or even lactonic counterparts.

公开(公告)号：US20250025563A1

公开(公告)日：2025-01-23

申请号：US18252394

申请日：2023-04-06

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： KEN ALIBEK ,  LEE SPEIGHT ,  ANDREW MORRIS ,  DANIEL HAGAMAN ,  SEAN FARMER

IPC: A61K47/54

Abstract: The present invention provides modified sophorolipids modified with amino acids to improve, e.g., the bioavailability of the amino acids. The modified sophorolipids of the present invention are capable of efficiently delivering the amino acids to the target site and enhancing the efficacy of the amino acid and/or the sophorolipids.

公开(公告)号：US20240425488A1

公开(公告)日：2024-12-26

申请号：US18248441

申请日：2023-03-08

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： LEE SPEIGHT ,  DANIEL HAGAMAN ,  ANDREW MORRIS ,  AYENDA ZEMAITIS

IPC: C07D407/12 ,  C07F1/04 ,  C07F1/06 ,  C07F3/02 ,  C07F3/04

Abstract: The present invention provides modified sophorolipids comprising taurine for improved foaming performance. The present invention also provides compositions comprising the modified sophorolipids formulated for cosmetics and personal care products. Further provided are methods for improving skin conditions, enhancing and/or maintaining the oral health, and cleaning, enhancing and/or maintaining heathy hair of a subject.

公开(公告)号：US20240366489A1

公开(公告)日：2024-11-07

申请号：US18248380

申请日：2023-01-28

Applicant: LOCUS SOLUTIONS IPCO, LLC

Inventor： LEE SPEIGHT ,  AYENDA ZEMAITIS ,  DANIEL HAGAMAN ,  SEAN FARMER

IPC: A61K8/60 ,  A61K8/34 ,  A61K8/35 ,  A61K8/37 ,  A61K36/06 ,  A61Q3/04

Abstract: In one aspect, the invention pertains to a nail polish remover composition comprising a glycolipid to reduce the occurrence of dry and/or irritated skin as well as dry nails adjacent to the nails, and/or hydrate the skin and nails. The presence of glycolipids in the composition further facilitates wetting of the nail care product and removal of the product from the nail. In another aspect, the present invention pertains to a treatment composition and method of using such composition to hydrate nails and surrounding skin and/or treat a fungal infection of hands and feet.