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1.发明申请POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY 有权具有控制释放速率和形态的POLY（ESTER AMIDE）-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY公开(公告)号：US20110153004A1
公开(公告)日：2011-06-23
申请号：US13037173
申请日：2011-02-28
申请人： LOTHAR WALTER KLEINER , JESSICA RENEE DESNOYER , STEPHEN DIRK PACETTI , SYED FAIYAZ AHMED HOSSAINY
发明人： LOTHAR WALTER KLEINER , JESSICA RENEE DESNOYER , STEPHEN DIRK PACETTI , SYED FAIYAZ AHMED HOSSAINY
CPC分类号： A61L27/34 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02
摘要： A method of forming a coating on a medical device having a controlled morphology is described. A method of treating a disorder in a patient using the medical device is described.
摘要翻译： 描述了在具有受控形态的医疗装置上形成涂层的方法。 描述了使用医疗装置治疗患者的病症的方法。
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公开(公告)号：US20080206306A1
公开(公告)日：2008-08-28
申请号：US12114645
申请日：2008-05-02
IPC分类号： A61F2/82
CPC分类号： C08G69/44 , A61K47/593 , A61K47/595 , A61K47/64 , A61L27/34 , A61L31/10 , C08L77/12
摘要： Provided herein is a copolymer that includes a soft block (A) and a hard block (B) comprising a tyrosine di-peptide. The copolymer can be any of AB, ABA or BAB type block copolymers. The soft block can include a PEA polymer. A coating formed of the copolymer may also include a bioactive agent. The implantable device can be implanted in a patient to treat, prevent, or ameliorate a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, and/or tumor obstruction.
摘要翻译： 本文提供了包含软嵌段（A）和包含酪氨酸二肽的硬嵌段（B）的共聚物。 共聚物可以是AB，ABA或BAB型嵌段共聚物中的任一种。 软块可以包括PEA聚合物。 由共聚物形成的涂层也可以包括生物活性剂。 可植入装置可以植入患者体内以治疗，预防或改善诸如动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉吻合增殖等障碍 人工移植物，胆管阻塞，输尿管梗阻和/或肿瘤阻塞。
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公开(公告)号：US20080293893A1
公开(公告)日：2008-11-27
申请号：US12186415
申请日：2008-08-05
IPC分类号： C08L77/04
CPC分类号： C08G69/44 , A61K47/593 , A61K47/595 , A61K47/64 , A61L27/34 , A61L31/10 , C08L77/12
摘要： Provided herein is a copolymer that includes a soft block (A) and a hard block (B) comprising a tyrosine di-peptide. The copolymer can be any of AB, ABA or BAB type block copolymers. The soft block can include a PEA polymer.
摘要翻译： 本文提供了包含软嵌段（A）和包含酪氨酸二肽的硬嵌段（B）的共聚物。 共聚物可以是AB，ABA或BAB型嵌段共聚物中的任一种。 软块可以包括PEA聚合物。
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