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公开(公告)号：US11493512B2
公开(公告)日：2022-11-08
申请号：US15373669
申请日：2016-12-09
发明人： Paul Scott Eastman , Eric Sasso
摘要： Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
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2.发明公开公开(公告)号：US20240295553A1
公开(公告)日：2024-09-05
申请号：US18424298
申请日：2024-01-26
发明人： Paul Scott Eastman , Eric Sasso
IPC分类号： G01N33/564 , C12Q1/6883 , G09B7/00 , G16B40/00 , G16B40/20
CPC分类号： G01N33/564 , C12Q1/6883 , G09B7/00 , G16B40/20 , C12Q2600/118 , C12Q2600/158 , G01N2800/102 , G01N2800/56 , G01N2800/60 , G16B40/00
摘要： Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
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公开(公告)号：US20220057394A1
公开(公告)日：2022-02-24
申请号：US17464061
申请日：2021-09-01
发明人： Paul Scott Eastman , Eric Sasso
摘要： Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
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公开(公告)号：US20230142317A1
公开(公告)日：2023-05-11
申请号：US17917887
申请日：2021-04-08
发明人： Darl Flake , Eric Sasso
IPC分类号： G16H50/50
CPC分类号： G16H50/50
摘要： Methods for evaluating the risk of radiographic progression in a subject with RA are provided. Also provided are methods of determining treatment efficacy for a subject with RA. Methods of selecting a treatment regimen for a subject with RA are also provided.
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