公开(公告)号：US20060082363A1

公开(公告)日：2006-04-20

申请号：US10993964

申请日：2004-11-18

申请人： Lamar Ricks ,  Ryan Furio ,  Andrew Nicol

发明人： Lamar Ricks ,  Ryan Furio ,  Andrew Nicol

IPC分类号： G01P3/46

CPC分类号： G01D5/142 ,  G01D3/022 ,  G01D5/24452 ,  G01D5/2449

摘要： A position detection system and method for linear and rotary sensing applications are disclosed herein, including a plurality of magnetoresistive sensing components for linear and rotary detection sensing, and an integrated circuit for amplifying and calibrating signals generated by the magnetoresistive sensing components in order to provide a full digital calibration and a ratio-metric output voltage or digital output signal indicative of linear and rotary position data.

摘要翻译： 本文公开了用于线性和旋转感测应用的位置检测系统和方法，包括用于线性和旋转检测感测的多个磁阻感测部件，以及用于放大和校准由磁阻感测部件产生的信号的集成电路，以便提供 全数字校准和比例度量输出电压或指示线性和旋转位置数据的数字输出信号。

公开(公告)号：US20140120503A1

公开(公告)日：2014-05-01

申请号：US14063426

申请日：2013-10-25

申请人： Andrew Nicol ,  Gabriel Salinas

发明人： Andrew Nicol ,  Gabriel Salinas

IPC分类号： G09B5/02 ,  G06F17/28 ,  G06F17/21

CPC分类号： G09B5/02 ,  G06F17/2827

摘要： The system platform and methods of the present disclosure brings the dual language concept to electronic books in a manner enhanced for both visual and aural learners. A method can include creating a correspondence between a first language text and a second language text. The method can include creating a correspondence between the first language text and an audio recording of the first language text. The method can include generating a dual language electronic book file comprising the first language text, the second language text, the correspondence between the first language text and the second language text, and the correspondence between the first language text and the audio recording of the first language text. An application for electronic book reading devices displays the text while playing the audio recording, maximizing the number of fragments of the first and second language texts based on one or more display variables.

摘要翻译： 本公开的系统平台和方法将双语言概念以对于视觉和听觉学习者的增强的方式带给电子书。 方法可以包括创建第一语言文本和第二语言文本之间的对应关系。 该方法可以包括在第一语言文本和第一语言文本的音频记录之间建立对应关系。 该方法可以包括生成包括第一语言文本，第二语言文本，第一语言文本和第二语言文本之间的对应关系的双语言电子书文件以及第一语言文本与第一语言文本的音频记录之间的对应关系 语言文字。 电子书阅读装置的应用在播放音频记录时显示文本，基于一个或多个显示变量最大化第一和第二语言文本的片段数量。

公开(公告)号：US08609410B2

公开(公告)日：2013-12-17

申请号：US12066313

申请日：2006-09-05

申请人： Mie Nieda ,  Manami Isogai ,  Masashi Takahara ,  Andrew Nicol

发明人： Mie Nieda ,  Manami Isogai ,  Masashi Takahara ,  Andrew Nicol

IPC分类号： C12N5/078 ,  C12N5/0784

CPC分类号： C12N5/0639 ,  A61K38/00 ,  A61K39/0011 ,  A61K2039/5158 ,  C12N5/0636

摘要： Activated antigen-presenting cells that can induce immunocytes including disease antigen-specific CD8+ CTLs and/or γδ T cells efficiently in vivo and/or in vitro, a medical composition comprising the activated antigen-presenting cells, a treatment and prevention method using the activated antigen-presenting cells, and an induction method of immunocytes including disease antigen-specific CTLs and/or γδ T cells induced using the activated antigen-presenting cell, immunocytes induced by the above-noted method, a medical composition comprising the immunocytes, and a treatment and prevention method using the immunocytes are provided. By co-pulsing antigen-presenting cells with bisphosphonate in addition to the pulse with a disease antigen, the ratio of disease antigen-specific CD8+ CTLs and/or γδ T cells and the number of the disease antigen-specific CD8+ CTLs and the γδ T cells can be increased, compared with the case where the co-pulse with bisphosphonate is not carried out.

摘要翻译： 可在体内和/或体外有效诱导包括疾病抗原特异性CD8 + CTL和/或Gammadelta T细胞的免疫细胞的活化抗原呈递细胞，包含活化的抗原呈递细胞的药物组合物，使用活化的抗原呈递细胞的治疗和预防方法 抗原呈递细胞，以及包括使用活化的抗原呈递细胞诱导的疾病抗原特异性CTL和/或Gammadelta T细胞的免疫细胞的诱导方法，由上述方法诱导的免疫细胞，包含免疫细胞的药物组合物和 提供了使用免疫细胞的治疗和预防方法。 除具有疾病抗原的脉冲之外，通过将抗原呈递细胞与双膦酸盐共脉冲，疾病抗原特异性CD8 + CTL和/或Gammadelta T细胞的比例以及疾病抗原特异性CD8 + CTL和gammadelta T的数量 与不进行与双膦酸盐的共脉冲的情况相比，可以增加细胞。

公开(公告)号：US20090104161A1

公开(公告)日：2009-04-23

申请号：US12066313

申请日：2006-09-05

申请人： Mie Nieda ,  Manami Isogai ,  Masashi Takahara ,  Andrew Nicol

发明人： Mie Nieda ,  Manami Isogai ,  Masashi Takahara ,  Andrew Nicol

IPC分类号： A61K45/00 ,  C12N5/08 ,  A61P35/00 ,  C07F9/02

CPC分类号： C12N5/0639 ,  A61K38/00 ,  A61K39/0011 ,  A61K2039/5158 ,  C12N5/0636

摘要： Activated antigen-presenting cells that can induce immunocytes including disease antigen-specific CD8+ CTLs and/or γδ T cells efficiently in vivo and/or in vitro, a medical composition comprising the activated antigen-presenting cells, a treatment and prevention method using the activated antigen-presenting cells, and an induction method of immunocytes including disease antigen-specific CTLs and/or γδ T cells induced using the activated antigen-presenting cell, immunocytes induced by the above-noted method, a medical composition comprising the immunocytes, and a treatment and prevention method using the immunocytes are provided. By co-pulsing antigen-presenting cells with bisphosphonate in addition to the pulse with a disease antigen, the ratio of disease antigen-specific CD8+ CTLs and/or γδ T cells and the number of the disease antigen-specific CD8+ CTLs and the γδ T cells can be increased, compared with the case where the co-pulse with bisphosphonate is not carried out.

摘要翻译： 可在体内和/或体外有效诱导包括疾病抗原特异性CD8 + CTL和/或Gammadelta T细胞的免疫细胞的活化抗原呈递细胞，包含活化的抗原呈递细胞的药物组合物，使用活化的抗原呈递细胞的治疗和预防方法 抗原呈递细胞，以及包括使用活化的抗原呈递细胞诱导的疾病抗原特异性CTL和/或Gammadelta T细胞的免疫细胞的诱导方法，由上述方法诱导的免疫细胞，包含免疫细胞的药物组合物和 提供了使用免疫细胞的治疗和预防方法。 除具有疾病抗原的脉冲之外，通过将抗原呈递细胞与双膦酸盐共脉冲，疾病抗原特异性CD8 + CTL和/或Gammadelta T细胞的比例以及疾病抗原特异性CD8 + CTL和gammadelta T的数量 与不进行与双膦酸盐的共脉冲的情况相比，可以增加细胞。

公开(公告)号：US07173414B2

公开(公告)日：2007-02-06

申请号：US10993964

申请日：2004-11-18

申请人： Lamar F. Ricks ,  Ryan R. Furio ,  Andrew Nicol

发明人： Lamar F. Ricks ,  Ryan R. Furio ,  Andrew Nicol

IPC分类号： G01B7/30

CPC分类号： G01D5/142 ,  G01D3/022 ,  G01D5/24452 ,  G01D5/2449

摘要： A position detection system and method for linear and rotary sensing applications are disclosed herein, including a plurality of magnetoresistive sensing components for linear and rotary detection sensing, and an integrated circuit for amplifying and calibrating signals generated by the magnetoresistive sensing components in order to provide a full digital calibration and a ratio-metric output voltage or digital output signal indicative of linear and rotary position data.

摘要翻译： 本文公开了用于线性和旋转感测应用的位置检测系统和方法，包括用于线性和旋转检测感测的多个磁阻感测部件，以及用于放大和校准由磁阻感测部件产生的信号的集成电路，以便提供 全数字校准和比例度量输出电压或指示线性和旋转位置数据的数字输出信号。