公开(公告)号：US20100298594A1

公开(公告)日：2010-11-25

申请号：US12468585

申请日：2009-05-19

申请人： Larry E. Brammer, JR. ,  Barbara E. Fair ,  Cheng-Sung Huang ,  Linh Quach ,  Peter E. Reed ,  Leonard M. Ver Vers

发明人： Larry E. Brammer, JR. ,  Barbara E. Fair ,  Cheng-Sung Huang ,  Linh Quach ,  Peter E. Reed ,  Leonard M. Ver Vers

IPC分类号： C07C67/03

CPC分类号： C07C213/06 ,  C07C219/08

摘要： A method and apparatus for preparing a N,N-dialkylaminoalkyl acrytate in a continuous transesterification reaction. The reaction involves adding alkyl acrylates such as methacrylate or ethacrylate to a reboiler mechanism and efficiently removing alcohol co-products. Because the reaction is continuous, the alkyl acrylates can be added as needed to increase output, decrease output, or fine-tune the reaction dynamics. An entrainer is used to form a volatile azeotrope which contains both alcohol and entrainer and which is easily removed from the reboiler mechanism. This method reduces the amount of entrainer needed per unit of alkyl acrylate used and eliminates any need to purify the end product from entrainer contamination of the resulting N,N-dialkylaminoalkyl acrylate product.

摘要翻译： 在连续酯交换反应中制备N，N-二烷基氨基烷基丙烯酸酯的方法和装置。 该反应包括将丙烯酸烷基酯如甲基丙烯酸酯或乙基丙烯酸酯加入到再沸器机理中并有效地除去醇共同产物。 因为反应是连续的，所以可以根据需要添加丙烯酸烷基酯以增加产量，降低产量或微调反应动力学。 使用夹带剂形成含有醇和夹带剂并易于从再沸器机构中除去的挥发性共沸物。 该方法减少了每单位使用的丙烯酸烷基酯所需的夹带剂量，并且消除了任何需要净化最终产物对所得的N，N-二烷基氨基烷基丙烯酸酯产物的夹带剂污染。

公开(公告)号：US20110178327A1

公开(公告)日：2011-07-21

申请号：US12691159

申请日：2010-01-21

申请人： Barbara E. Fair ,  Peter E. Reed ,  Leonard M. Ver Vers ,  Larry E. Brammer, JR. ,  Charles J. Holada ,  Cheng-Sung Huang ,  Kailas B. Sawant

发明人： Barbara E. Fair ,  Peter E. Reed ,  Leonard M. Ver Vers ,  Larry E. Brammer, JR. ,  Charles J. Holada ,  Cheng-Sung Huang ,  Kailas B. Sawant

IPC分类号： C07C227/00

CPC分类号： C07C213/08 ,  C07C219/08

摘要： The invention provides a method of continuously producing high quality quaternized N,N-dialkylaminoethyl (meth)acrylates (DMAEA.MCQ) that has a long shelf life and which is stable in water. The method involves placing starting materials into a continuously stirred tank reactor in the presence of less than 6% water. This low amount of water causes two liquid phases to form and prevents unwanted side reactions. The denser liquid phase contains DMAEA.MCQ and the lighter phase contains the starting materials. Liquid from the denser phase is removed from a position where little of the lighter phase has been mixed in. The removed liquid then has any last traces of the starting materials reacted into DMAEA.MCQ and strips away any starting materials with a gas flow. The resulting liquid is high purity DMAEA.MCQ. Water can then safely be added to ease in the transport and use of the produced DMAEA.MCQ.

摘要翻译： 本发明提供了一种连续生产高效季铵化N（N-二烷基氨基乙基（甲基）丙烯酸酯（DMAEA.MCQ））的方法，其具有长的保质期，并且在水中稳定。 该方法包括在少于6％的水的存在下将原料放入连续搅拌的罐式反应器中。 这种少量的水导致形成两个液相并防止不期望的副反应。 密度较高的液相含有DMAEA.MCQ，较浅的相含有原料。 来自较稠相的液体从少量较轻相混合的位置被除去。然后，除去的液体具有反应成DMAEA.MCQ的起始材料的任何最后痕迹，并用气流剥离任何起始材料。 所得液体为高纯度DMAEA.MCQ。 然后可以安全地加入水，以便于运输和使用生产的DMAEA.MCQ。